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Case Study:  premature ejaculation, erectile dysfunction, less concentration, impatience, anxiety, aggression, less confidence, hatred, dark eye circles and sexual addition (persistence sexual arousal) can induce by low serotonin (melatonin), oxytocin, dopamine and cortisol level with a high level of glutamate, histamine, prolactin, testosterone and DHEA
Reader: 3/03/2008>


1. ok doctor, so you understand why my penis is extremely sensitive and erection is so weak even though my testosterone level is very high. even my testosterone level is so high i do not get any erections at all, no morning erections, very weak erections with stimulation only and ejaculation instantly. my penis only erects upto 6 inches n erections are very weak
 
2. does the blood test results explain sexual addiction? i get sexual addiction attack after few days which make me wants to look at porn and ejaculation urgency!? These attack usually attacks me at night when i go to sleep, they wake up after 30 mins - 1 hour and then i have severe urgency to look at porn and ejaculate, i cant go to sleep when these attacks strike me!!
 
3) does the blood test explain my no concentration and my brain is constantnly thinking....i have great impatience, anger, agression, hate, no feelings of love, depression, no confidence, my brain is thinking 24/7 it dont let me concentrate!
 
4) i know i have dark circles because of excess histamine, sometimes these dark circles reduce but sometimes they become more noticeable why is that? if my histamine level reduces, will my dark circles improve?

Measured value

Result

Time

Optimal Range

Therapeutic Range

Observed Range

Estradiol-Saliva
(pg/ml)

0.7

08:00 AM

Female:
Follicular: 0.5-5.0
Midcycle: 2.0-7.0
Luteal: 0.2-5.0
Menopause: 1.0-2.0
Male: 0.8-1.5

Not established

Female:
Follicular: 0.5-5.0
Midcycle: 2.0-7.0
Luteal: 0.2-5.0
Menopause (No HRT): <0.75
Male: 0.1-3.2

Estrone-Saliva
(pg/ml)

1.3

08:00 AM

Female:
Follicular: 0.5-3.5
Luteal: 1.0-4.5
Menopause: 1.0-3.0
Male: 1.0-2.5

Not established

Female:
Follicular: 0.5-3.5
Luteal: 1.0-4.5
Menopause (No HRT): 0.5-3.0
Male: 0.5-3.9

Progesterone-Saliva
(ng/ml)

0.046

08:00 AM

Female:
Follicular: <0.100
Luteal: 0.100-0.500
Menopause: 0.200-0.500
Male: 0.070-0.150

Not established

Female:
Follicular: <0.100
Luteal: 0.100-0.500
Menopause (No HRT): 0.030-0.080
Male: 0.030-0.060

Testosterone, Saliva*
(pg/ml)

122.3

08:00 AM

Female: 15-35
Male: 75-95
PM concentrations for Testosterone are significantly lower than AM concentrations

Not established

Female: 5-35
Male: 60-125
PM concentrations for Testosterone are significantly lower than AM concentrations

Dihydrotestosterone-Saliva
(pg/ml)

8.8

08:00 AM

Female: 5-12
Male: 20-40

Not established

Female: 1-8
Male: 10-50

DHEA-Saliva*
(pg/ml)

1137.5

08:00 AM

Female: 200-400
Male: 250-450
Prepubescent: 50-300
*PM concentrations for
DHEA can be significantly
lower than AM concentrations

Not established

Female: 80-1100
Male: 100-1200
*PM concentrations for DHEA can be significantly lower than AM concentrations

Cortisol-Saliva
(ng/ml)

4.8

08:00 AM

2-4 AM: <1.0
7 AM: 7.0-10
Noon: 3.0-6.0
5 PM: 2.0-4.0
10 PM: <1.5

N/A

7 AM: 8.0-15
Noon: 3.0-7.0
5 PM: 2.0-4.0
10 PM: <1.5
2-4 AM: <1.0

2.3 

12:30 PM

1.2 

06:05 PM

0.8 

10:45 PM

Epinephrine-Urine
(g/gCr)

8.9

09:30 AM

Day: 8-12
Night: 1-3

Day: 8-13
Night: 1-3

Day: 1-15
Night: <3

Norepinephrine-Urine
(g/gCr)

40.1

09:30 AM

Day: 35-50
Night: 20-30

Day: 30-75
Night: 20-30

Day: 15-106
Night: 15-40

Dopamine-Urine
(g/gCr)

89.1

09:30 AM

Day: 110-175
Night: 80-120

Day: 200-350
Night: 125-250

Day: 50-350
Night: 45-250

Serotonin-Urine
(g/gCr)

95.6

09:30 AM

Day: 150-200
Night: 100-175

Day: 200-700
Night: 120-250

Day: 40-275
Night: 25-250

GABA-Urine
(umol/gCr)

2.8

09:30 AM

Day: 1.5-4.0
Night: 1-3

Day: 5-10
Night: 5-8

Day: 1.5-35
Night: 1.5-20

Glutamate - Urine
(umol/gCr)

40.2

09:30 AM

Day: 10-35
Night: 8-20

N/A

Day: 5-65
Night: 5-35

PEA-Urine
(nmol/gCr)

264.0

09:30 AM

Day: 175-450
Night: 125-300

N/A

Day: 140-1200
Night: 100-350

Histamine-Urine
(ug/gCr)

19.4

09:30 AM

Day: 10-20
Night: 5-15

N/A

Day: 9.0-60
Night: 2.5-20

Creatinine-Urine
(mg/dL)

219.7

09:30 AM

N/A

N/A

N/A

Measured value

Result

Time

Optimal Range

Therapeutic Range

Observed Range


Dr. Lin: 3/03/2008>
1. Yes, A high histamine, testosterone and glutamate  level give you a very high sensitive penis;  a low serotonin level with a high testosterone level give you anxiety, aggression, depression and impatience, and a low dopamine level can not stimulate your endorphin and oxytocin release in your pituitary, testicles, prostate and penis.  A low cortisol level fails to suppress the production of prostaglandin E2 and histamine during sex, leading to over-sensitization of your prostate, penile and urethral nerves. Your high testosterone DHEA level generally over-counterbalance the adrenal cortisol production. OK, here is the sympathetic nervous erectile mechanism:  epinephrine/norepinephrine + oxytocin activate the sympathetic nervous adrenergic beta receptors for penile arteries dilation and hard erection, while epinephrine/norepinephrine + prolactin activate the alpha-2 receptors to constrict the penile arteries for the penis to go limp, like your post-ejaculation penile state, even if your testosterone and DHEA are very high. When your oxytocin is too low, you feel hatred.
2. Yes. A high histamine, glutamate, testosterone and DHEA level triggers excessive prostaglandin E2 production for persistent sexual arousal and addiction, even if your dopamine level is too low
3. Yes. a high histamine, testosterone and DHEA with a low serotonin nervous modulation.
4. it is due to excessive  histamine and glutamate,  insufficient sleeping (melatonin),  and arterial constriction around the eyes. You also experience allergic symptoms.
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