Thyroid Function vs. Erectile Function - The effect Hypothyroidism and Hyperthyroidism on Endothelium-dependent Vasodilation and Arterial Nitric Oxide Release and cGM Formation

Thyroid disorders can not only affect the metabolism and cardiovascular function, but also cause erectile dysfunction by alternating the capacities for both formation of and responding to NO in a rat arterial vessel.  according to McAllister et. al.,  hyperthyroidism can be associated with increased capacity for NO formation, but reduced capacity for responding to NO, compared with hypothyroidism state. Capacity for NO formation, assessed by NOS activity, is primarily a property of the vascular endothelium. Capacity for responding to NO, estimated by NO donor-stimulated concentration of cGMP, resides in vascular smooth muscle. The research conclude that thyroid status affects more than the endothelial layer of the vascular wall, . Thus, thyroid disorders can stiffen the arteries for erectile dysfunction and coronary artery disease.  As for sex,  the patients may fail to testosterone replacement therapy or/and PDE-5 erectile drugs.  Anti-oxidant Alpha-lipoic acid and magnesium may help improve the nitric oxide and cGM release.

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Hyperthyroidism is likely to over-stimulate the sympathetic nervous function for Fight or/and Flight responses, leading to performance anxiety. Hypothyroidism understimulates the sympathetic nervous erectile function, leading to using the PC muscles contraction for assisting erection. Overuse of the PC muscles trains the L1 and L2 nervous reflexion arc for fast orgasm and ejaculation.  Thyroid status alternates the autonomic nervous function, where hyperthyroidism stimulates the sympathetic nervous function to overpower the parasympathetic while hypothyroidism causes deficiency of the dopamine and parasympathetic nervous function

Case Examples:
Over-Masturbation can exhaust the hypothalamus-pituitary-thyroid axis for hypothyroid that hardens the arteries and reduce the blood circulation for retarded healing of clitoral/vaginal nervous and tissues damage, burning pains, sleeping disorders, stress
Cause and solution for orgasm-induced abdominal cramps, tailbone pain, digestive panic responses, diarrhea, irritable bowel syndrome, and rectal incontinence 
Hypothyroid functions cause low testosterone production, low libido, impotence, low energy, lack of focus and low mood. Why estradiol and its metabolites are harmful? 
Thyroid disorders (hypothyroidism, or "hyperthyroidism induced by T3 medication") with high T3, but low TSH and T4, under T3 or T4 medication drugs, causes the hypothalamus-pituitary-adrenal and -testicular functional disorder for low libido , erectile dysfunction, muscle and joint aches (arthritis), fatigue, loss of concentration, and sleeping disorders. It may be due to liver and kidney functional disorders with excessive 5'-deiodinas in the bloodstream 
Either hyperthyroidism or hypothyroidism causes weak erection and premature ejaculation. 
Chronic over-masturbation sent him to Emergency Room with breathing difficulty, racing heart, panic attack, chest and body pains (and, of course, a shrunk penis), but the doctors found nothing wrong! 
Hypothalamus-pituitary-adrenal, -thyroid and -ovarian disorders cause androgen hormone deficiency for excessive Vaginal White discharge, vaginal immune disorder, yeast or fungal (candida) infection, Chronic Fatigue Syndrome and Fibromyalgia for no more sex or sexual orgasm - solution 
Finasteride killed his sex, semen production, erection and sexual orgasm 
A 29-years old woman's experiences in side effects of birth control pills for no sexual orgasm, but low libido, love breakup, chronic vaginosis, chronic fatigue, foggy brain, depression, vaginal fishy discharge, intercourse pains / Vaginismus / Dyspareunia, vaginal and vulva inflammation, Vulvodynia / Vestibulitis, physical weakness, hypothyroidism, ... 
Myalgic Encephalomyelitis or hypothalamic-pituitary-adrenal fatigue - solution. Mistreatment with SSRIs antidepression drugs result in dead clitoris and vagina for no more sexual orgasm 
Finasteride killed his sex and semen production for hypothyroid and sent his estrogen level over the roof for no libido and no sexual orgasm 
Teenager's crazy experiences with Ecstacy (MDMA) and over-masturbation for no more sexual orgasm. 
Hypothyroidism, libido and sexual orgasm 
Hyperthyroid, acetylcholine, erectile dysfunction and sexual orgasm 

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