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Case Study:   Chronic masturbation, followed vasectomy, causes orgasm headaches, hot flushes, dizziness, irregular heart beat, eye pressure, neck stiffness, testicular aches, frequent urinary with a weak/slow stream, urine leakage, cold sensation, eye floaters, IBS, memory loss, ear ringing, low libido, mood swing, anxiety and hypertension for no sexual orgasm
Reader: 2/07/2011>
Hello my name is carl
I had given up looking for answers a long time ago putting it down to this is the way it is.i hope you can help me My wife came across an article in a women’s magazine doctors section based around a sexual headache. Which suggested overproduction of prostaglandin E2 which in turn took me looking into a new direction and led me to your web site? Reading a lot of your case studies led me to the conclusion there is light at the end of the tunnel but noticing what you suggest to each case as supplements vary a lot depending on their symptoms. So looking for what supplements would help me and dosage
I live in England, United Kingdom 43 year old male I consider myself active as I cycle to work for the past 10 years approx 80 miles a week I eat well and take daily multivitamins and minerals plus linseed oil 5 days a week have done for years now
From the age of about 13 masturbation was at least once a day then from my twenties till around six months ago every day and up to 2/3 time in one day but not in a row of days (porn) Never done drugs and always been light drinker go months without a drink at a time Gave up smoking 3 months before event smoked for 15 years.
I had a vasectomy approx 10 years ago the chances of it going wrong was 1 in a 1000 I was the 1 still had a semen count so had it done again but this time developed a infection left side never been the same again when aches always seems to be on left side. Six years ago leading just before reaching a orgasm with my wife I got a intense sharp pain pulsed with heart beat at the base of my scull left-hand side thought my head was going to explode I had no warning it was coming I stopped my activity for a while and tried again to orgasm but could feel pressure building up and could not go on. I then had bad headaches (like pressure behind the eyes aching jaw ) hot flushes ,dizziness irregular heart beat to the point they put me on beater blockers . I went to my doctors explaining what had happened they admitted me to hospital ran tests had a scan but could not find anything or give me a diagnoses. Now six years on headaches/migraines are the main problem I cannot deal with stress if I get stressed my neck muscles tense up and lead to a headache/migraines which lasts for days/weeks , Masturbation/sex as it stands now average 5 times a week sometimes odd day 2 times in one day.
If I take a laid back approach I can orgasm but if I over assert myself in the bedroom with my wife ill end up with the big thumper before I get to orgasm and will be unable to reach orgasm because of the pain being to severe Symptoms as they stand now
Headache varies from feeling pressure build up /sharp pain behind 1 eye (wake up with most of time)//Very stiff neck most of the time/testicles ache from time to time Urinating often/urine feels restricted -slow/ urine leakage /cold sensation//Eye floaters //Dizziness time to time // Stomach problems (IBS like) // long term and short term memory loss (take a phone message turn around to pass on and its gone)// ear ringing (not often)// lost drive // mood swings//anxiety//blurry vision//hypertension
thank you for taking the time to read
Dr. Lin: 2/07/2011>
You got the typical sexual exhaustion symptoms, as listed in
yes, You will  need ViaPal-hGH-E(3-014) and ArgiNOx (1-018), plus FishOil(1000 mg each meal) and Vitamin D 2000 IU,  to help you gradually rejuvenate your neuro-endocrine function and  boost your prostaglandin E-1/E-3 and Nitric Oxide production for healing.

Your problems are a result of androgen (testosterone) deficiency, weak serotonin and GABA nervous control on the hypothalamus-pituitary-adrenal axis and the sympathetic nervous fires,  and excessive hypothalamic and adrenal dopamine-norepinephrine conversion for induction of excessive inflammatory hormone prostaglandin E2 release from your head/eyes/ears down to your prostate, bladder and  feet.

Why?  Consider the Sexual Arousal Neuroimmune Pathway: The dopamine nervous system stimulates the hypothalamus-pituitary axis, with orchestral effects of androgen hormones DHEA/testosterone/DHT (,Pfaus,Wenkstern,Phillips,Fibiger%20(1992)%20Behav%20Neurosci.pdf, , ),  to activate the norepinephrine/sympathetic nervous action and the oxytocin, NOergic (NO = Nitric Oxide - released from the parasympathetic nervous endings)  and prostaglandin E2 stimulation on sex organs (prostate, seminal vesicles, penis and testicles, clitoris, uterus, vagina and ovaries), leading to the induction of swelling/congestive/inflammatory  pressure, arterial dilation and nervous sensitivity.  The swelling/congestive/inflammatory pressure won't give you pain, but nervous sensitivity if the tissues release sufficient prostaglandins E1 and E3 to relax the nerves and blood vessels and to enhance their elasticity and flexibility.  This is how sexual desire initiates and how people experience the persistent sexual arousal symptom. Noticeably, the highly stretched penile nerves may be desensitized when a penis is ballooned into the 2nd stage erection where the erecting penis becomes about 120% bigger than the initial erection. This exception can be achieved by the penile ballooning enlargement where prostaglandins E1/E2/E3,  androgen hormones, oxytocin, histamine, sympathetic and parasympathetic nervous erectile mechanism are synchronically working together.   Before sexual exhaustion, prostaglandin E2, with oxytocin and histamine,  acts as a vasodepressor/vasodilator; after sexual exhaustion, it, with a high level of prolactin and a lack of oxytocin and NO release,  becomes vasopressor/vasoconstrictor and arterial/venous narrowing  imflammator,  even with a high level of histamine. The tricky roles of prostaglandin E2 are also described in .  Men or women can get a lot of erection, sex-organ swelling, and sexual desire from the stimulation of prostaglandin E2 (in conjunction with a high level of histamine release) with a high price - inflammatory body pains, congestive headaches, dizziness, or/and excessive, unwanted leakage/discharge out of the penis/vagina, if the cholinergic/vagal/serotonin/GABA nervous function, in conjunction with action of androgen hormones and prostaglandins E1 and E3,  are too weak to modulate the local inflammatory response induced by noradrenergic (norepinephrine)/sympathetic nervous fires (pyrogens) and prostaglandin E2 in the sympathetic adrenergic receptors.  In the brain, the hypothalamic dopamine-norepinephrine conversion during sexual arousal triggers endogenous pyrogens to act on the Organum Vasculation of the Lamina Terminalis of the third ventricle to promote prostaglandin E2 release to open the blood-brain barriers for more androgen hormones (stress hormones and toxins too!) to enter the brain and central nervous system, and to elevate the core temperature for sex heat. That is why you feel heat and warm when you become sexual arousal.  You may feel dizziness in your first encounter with a new partner. In the body, prostaglandin E2 promotes bradykinin-induced pains, spinal/back pains, the coagulation of platelets, bone resorption and formation (good!), immune disabling (for infection, but good for making babies: 1. de-activating the urethral, vaginal and uterine immune to help sperms survive through male ejaculation duct, female vagina, cervix, and uterus; 2. disabling the egg immune to help a sperm fertilize the egg; 3. disabling the uterine immune to allow the fertilized egg to be implanted or transplanted; 4. inducing labor (orgasms too)),  cancer and carcinogenesis, hypertension,  muscle protein degradation (muscular weakness and shrinkage), cardiovascular disorders, and synaptic neuroplasticity for alternation and reprogramming of brain/nervous functions (for better or worse), short-and long-term memory (including sexual pleasures!), addiction (of drug and sex!), alzheimer's disease, psychological disorders, and promotion of chronic noradrenergic/sympathetic fight or flight responses. You see, prostaglandin E2 plays the role of the good, the bad and the ugly in your life from the beginning to the end (death.)
Thus,  sex is a neuro-immune and hypothalamus-pituitary-adrenal and -testicular (-ovarian) challenge, good (constructive) or bad (destructive) depending on how you manipulate and perform it.  Sexual arousal or orgasm triggers the neuro-immuno-endocrine function for better or worse, depending on the immunoreaction of the noradrenergic (norepinephrine)/sympathetic nervous system to its resulted stress  and on the balance of its induced pro-inflammatory and anti-inflammatory responses. If you ignore the neuro-immune responses to sex-induced stressors norepinephrine and epinephrine, sex will destroy your health for no more orgasm, but pains and psychological disorders like drug abuse.  The neuro-immune-endocrine responses to sex-induced stress are driven by the sympathetic nervous alpha- and beta-adrenergic receptors of the immune cells which release immunotransitters cytockines and protein kinases for pro-inflammation or/and anti-inflammation.  The classic Taoism teaching considers sex as a powerful drug for better or worse, up to individual practices. 
Over-masturbation/over-ejaculation/excessive-orgasm castrate the hypothalamus-pituitary-testicular axis by arterial constriction and inflammatory narrowness in your brain and pelvic organs (testicles, prostate, seminal vesicles, penis, and so on) due to excessive release of prolactin, norepinephrine, and epinephrine, excessive binding of norepinephrine/epinephrine on the alpha-adrenergic receptors, the norepinephrine/epinephrine induced excessive prostaglandin E2, and the post-sex deficiency of nitric oxide and prostaglandins E1/E3 production. As a result of arterial constriction and inflammatory narrowness (leading to  arterial thrombosis and atherothrombosis!;  ),  your brain, ears, eyes, testicles, penis,   feet and hands get low blood supplies and less androgen hormones and nuerochemicals, but more inflammatory hormone production and stress hormones.  And, it will take a long time for you to get recovery from sexual exhaustion and post-sex inflammation. You may also wonder why your  penis  goes limps  in the middle of sex.  When your adrenal and testicular  function are disabled, you will have to rely on the skin neruoendocrine function to elevate your androgen hormones.  Please also note that prostaglandin E2 also inflame veins too -,, and .  When you get inflamed arteries and veins, your blood circulation won't reach the inflamed areas and you will experience pain, numbness or cramp .