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Case Title:  Solution for Persistent Sexual Arousal Syndrome and interstitial cystitis induced by COX-2 over-expression and inflammatory hormone prostaglandin E-2 in the pelvic cavity tissue and for control of unwanted, spontaneous sexual orgasm
Reader: 7/15/2005>
Dear Sir:

About 6 months ago I was prescribed Gaabatril for anxiety. Within two days I had a bladder infection at which point I started a generic antibiotic and another drug called Elmironn. These came from my urologist ( have a long history of cystitis and interstitial cystitis ). Within a few days I had developed an extreme case of Persistent Sexual Arousal Syndrome. It was a horrible experience. Well it is better now but has never gone away. Ever since I took the Gabbatril my bladder and the sexual arousal situation have become debilitating. I am desperate. I read another letter on your site about this and I have started taking 5-htp and think that I am feeling some relief. My question is about your advice on taking Gaba. Since I think it was the Gabaatril that caused my problem I am reluctant to take Gaba without checking with you about that. Also at the current time I have a horrible bladder infection which does not seem to be responding to ppyridium which usually stops the discomfort right away. I have been on the antibiotic almost a week now without resolution to the problem. This is extremely unusual. Please tell me what to do and what products I need. You are the only person who seems to know what to do about this PSAS. Thank you.
Dr. Lin: 7/16/2005>Your Persistent Sexual Arousal Syndrome (PSAS) is a result of bladder/uterine/cervical (and/or clitoral) inflammation and swelling.  Our readers have reported that their inflamed clitoris causes out-of-control uncomforntable orgasms with pains.  The problem is: the sensory nerves in the inflammatory tissue in the urethra, bladder and sex organs continuously relays the stimulation signal produced inflammation to your brain's hypothalamus via the vagus, L1 and L2 circuits for sexual arousal and orgasm responses. You know it is a fake sexual stimulation signal, but you can not suppress it.  In some situations, the uterus/cervix will also move (relocate) to induce arousal or orgasmic uterine contraction in response to sex hormone changes or bladder inflammation or expansion
Since you have a long history of cystitis and interstitial cystitis (IC), the enzyme COX-2 in your pelvic cavity tissues should be very activity. Therefore, any medication drugs or antibiotics reducing the serotonin and GABA level in the local tissue or suppressing COX-1 expression, will further enhance COX-2 over-expression for more inflammatory hormone prostaglandin E-2 synthesis in the tissue. Thus, your PSAS will become worsen.  For more information on IC, please read http://www.actionlove.com/extra/ic.htm 
In my last advices to PSAS patients with unknown reasons, it requires a high dose of 5-HTP and GABA to modulate the pelvic sensory nervous sensing and transduction and the pituitary's oxytocin release.
On Persistent Sexual Arousal Syndrome for too much sexual orgasm -
Since your conditions are known, you can take ViaPal-hGH-E (3-011) with a high dose of Fish and Borage (or Eveneing Primrose) oil 1000 mg 3 times a day with each meal to reduce the prostaglandin E-2 synthesis and enhance the prostaglandin E-1 and E-3 synthesis for healing your problems, including PSAS, bladder infection and interstitial cystitis (IC).
By the way, PinealTonin in ViaPal-hGH-E contains 5-HTP (50 mg )and GABA (100 mg) with Cofactors for improving the nervous modulation and reducing the COX-2 expression. Your IC and PSAS conditions are to those experienced by men who have an excessive prostaglandin E-2 in the seminal vesicles, prostate and Cowper's (bulbourethral) glands and want sex and ejaculation all the times even they experiencing severely pelvic or pubic, low-back pains. The inflammatory conditions can cause women's excessive vaginal wetness and men's excessive precum or/and semen leakage.

Reader: 7/21/2005>
I had written you recently about getting psas after taking the drug gabatril and developing a bladder infection. (I have a history of interstitial cystitis.) I ordered the products you recommended but have not received them yet. I had 5-htp at home and started taking that. I felt a little relief. Then I went to the pharmacy and bought evening primrose. After just one day, I have noticed a marked improvement. This is the first relief of any significant amount that I have had in 6 months. Thank you so much!
Dr. Lin: 7/21/2005>
Yes. Your problem is a result of excessive inflammation hormone prostaglandin E-2 in your pelvic cavity.


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