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Case Title:  Chronic over-masturbating from age 14-31 results in all of the sexual exhaustion symptoms, some fatigue, graying of hair, hair thinning, eye floaters, sinus, ear aches, and sleeping disorder for no more sexual orgasm. On the arylalklamine N-acetyltransferase gene expression disorder in the pineal gland and retina for circadian rhythm and visual nervous disorders. Why can a good sex improve your health?
Reader:  1/23/2005>
I have been masturbating for 17 years now... 14-31. I have all of the symptoms, some fatigue, graying of hair, hair thinning, eye floaters, sinus and ear aches. Is it too late for me to heal this process. How often should I limit my masturbation. It has become the only way I can fall asleep. 
Dr. Lin: 1/23/2005>You has been sexually exhausted by your chronic over-masturbation/over-ejaculation. You have experienced the typical sexual exhaustion symptoms as listed in this link -
Destruction produced by Male over-ejaculation/over-masturbation or Female Over-Masturbation/excessive orgasm for no sexual orgasm.
Your chronic over-masturbation/over-ejaculation has burned out the acetylcholine/serotonin/GABA nervous function and then alternated the tyrosine hydroxylase, dopamine betab-hydroxylase and phenylethanolamine-N-methyl transferase gene expressions for excessive dopamine-norepeinephrine-epinephrine conversion in the brain and adrenal medulla, leading to sympathetic nervous Fight or/and Flight responses ( adrenomedullary function and stress/histamine response) and an over-expression of 5-alpah reducatase genes in the blood, adrenal cortex, prostate and testis for a constant testosterone-DHT conversion to heat up your blood for Fight or Flight actions.
In the brain, the excessive norepinephrine and epinephrine nervous action can constantly switch the autonomic nervous function from the parasympathetic mode to the sympathetic mode to burn your energy and exhaust your body. If there is excessive binding of norepinephrine and epinephrine  into the alpha-2 receptors, it results to constriction of the blood vessels (poor blood circulation), eye pupil over-dilation (like a dying person, eye over-sensitive to light) , COX-2 and Protein Kinase C (PKC) over-expression, and COX-1 under-expression for brain/nervous disorders/body pains/ eye floater (blurred vision)/sinus/earring aches. Your hot blood with a poor scalp circulation due to excessive DHT, norepinephrine and epinephrine has burned out your hair rooting cells and changed your hair color. The main concern is the excessive epinephrine (adrenalin) in the brain and bloodstream. An excessive dopamine-norepinephrine conversion for a excessive level of norepinephrine, as a result of  frequent sexual arousal or orgasm or excessive sex, can trigger excessive norepinephrine-epinephrine conversion for a constantly excessive adrenalin (epinephrine) level in the bloodstream. This is what the sexual exhaustion symptoms and nervous disorders come from. A normal sexual  orgasm or ejaculation usually triggers a moderate dopamine-norepinephrine conversion with a slight elevation of epinephrine, where the moderate norepinephrine elevation improves the neuro-immune function, good for health,  and triggers the pineal gland to convert serotonin into melatonin for a good sleep if your brain has enough 5-HTP and serotonin.  A slight elevation of epinephrine (adrenalin) gives a warm blood after sex for a few minutes (30-60 minutes, typically). Once the warming effect of epinephrine on the body dies down (or norepinephrine-epinephrine conversion stops), the elevation of the melatonin in the bloodstream takes over and then triggers a deep sleep for the acetylcholine/parasympathetic nervous function to restore your body and healing the injury. That is why a good sex life or orgasm can improve your health.  
However, if you have a deficiency of serotonin in 5-HT receptors, you will experience orgasm or post-orgasm/post-ejaculation headaches, stess, seizure-like or Parkinson-like response,  fatigue, or hot flashes.  Particularly, without the acetylcholine/serotonin nervous modulation in the pineal gland, the excessive epinephrine in your brain after an excessive norepinephrine-epinephrine conversion, with a drop of dopamine and norepinephrine,  will disable the expression of tryptophan hydroxylase (TPH, the serotonin synthetic enzyme), arylalklamine N-acetyltransferase (AANAT) and ARC (activity regulated, cytoskeleton associated protein) genes. AANAT is responsible for the conversion of serotonin to melatonin. An AANAT gene expression disorder results in the serotonin-melatonin conversion disorders and thus, sleeping disorder. AANAT is the key enzyme in the biosynthesis of melatonin in the pineal gland and retinal photoreceptors. Rhythmic AANAT activity drives rhythmic melatonin production in these tissues for a good sleep and parasympathetic nervous recharging, that includes shrinking your eye pupil back! When there is excessive norepinephrine and epinephrine or a lack of serotonin in your pineal gland and retina, AANAT can not express properly and convert serotonin into melatonin. The expression of AANAT gene in pineal gland is regulated by a photoneural (retinal) system that acts through the sympathetic adrenergic-cAMP-related mechanisms (with a moderate norepinephrine level as described above) in pinealocytes with concomitant stimulation by norepinephrine of sympathetic nervous beta-1 and alpha-1 receptors, in a mechanism of "AND gate" activation, but disabled by excessive norepinephrine and epinephrine of sympathetic nervous alpha-2 receptors. When your bloodstream contains excessive norepinephrine and epinephrine with a high lack of prolactin due to over-masturbation/over-ejaculation or excessive orgasm, the AAANAT gene become under-expressed and you are in sleeping disorder.  The most severe condition for chronic sleeping disorder (AANAT gene disorder) is due to an excessive epinephrine level with a  lack of dopamine, norepinephrine and serotonin in the brain while there is an excessive dopamine-norepinephrine-epinephrine conversion anytime. Also, excessive epinephrine in the blood can trigger the histamine receptors activity for allergy, sinus and formation of dark eye circles. The causes for this condition are chronic over-masturbation/over-ejaculation/excessive orgasm and street drugs abuse.  
The reason can get a sleep by masturbation is due to the GABA-GHB conversion in the post-ejaculation state, where GHB is bound into the GABA B receptors sites to drop the brain and body temperature for drowsiness. But, the GHB induced sleeping is not enough to promote the parasympathetic nervous action for healing and restoration, and will let you feel hanging over when you wake up.
You need ViaPal-hGH-M (3-014) with extra Fish/borage oil 1000 mg each with each meal, Calcium(200 mg)/Magnesium(100 mg)/Vitamin-D(100 IU) to help you rejuvenate your nervous function and stop hair loss and color change.

Please Note: The daily rhythm of melatonin synthesis of the pineal gland and retina is mainly modulated by serotonin, acetylcholine, dopamine,  norepinephrine, GABA, GHB, epinephrine (adrenalin), Glutamate, Ca++, Mg++,  5-HT receptors, cholinergic receptors, dopamine D1 & D2receptors ,  sympathetic alpha and beta  receptors,  GABA-A &-B receptors, and light colors. The modulation can be semi-permanently alternated by  medication or streets drugs and life style. 

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