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Case Title:  The cellular biochemistry of premature ejaculation for no more sexual orgasm.
Reader:  10/01/2004>
Dr. Lin,

I am 43 and live alone. I consider myself fit and healthy. My sex life consists mainly of masturbation. I had no problem in getting and maintaining an erection while masturbation. Recently, I visited a prostitute. I had great difficulty in getting an erection and it did not last long enough to complete intercourse. It's a very frustrating and humiliating experience. Am I having Erectile Dysfunction? Was it caused by anxiety? What can I do about it?

Also, I am not happy with the size of my penis. It's only 5" when erect. Is there any safe and natural way to enlarge the penis?

Dr. Lin: 10/02/2004>Yes. Sexual excitement or arousal can trigger an excessive dopamine-norepinephrine-epinephrine conversion in the hypothalamus (when the acetylcholine, serotonin and GABA nervous modulation are too weak or too exhausted to regulate the gene expression of the dopamine receptors, particularly, D1 and D2) and an excessive release of prolactin from the pituitary gland, leading to sympathetic nervous fires for Fight or Flight, when prolactin forces norepinephrine and epinephrine to bind into the sympathetic nervous alpha-2 receptors, with a deficient dopamine binding in its D2 receptors and an excessive dopamine binding in its D1 receptors.  Here, sympathetic nervous "Fight" = "premature ejaculation (urethral female ejaculation) or premature orgasm (for men and women)", and "Flight" = "impotence or erection withdraw" for sex.
Premature ejaculation occurs when your semen or/and precum contains excessive prostaglandin E-2 or/and  its 19-hydroxy-prostaglandin E-2 (due to the liver P450 enzyme 19-hydroxylase in semen), which excite the L1/L2 sympathetic nervous circuits and then, in turn, promotes further more over-expression of COX-2 in the tissue of the seminal vesicles, prostate and urethra for more prostaglandin E-2 synthesis for more sympathetic nervous fires, resulting in dilating the ejaculation duct and valve for semen and sperm emission. A long-term (a few days) semen retention can cause this problem with  pelvic and prostate congestion or pains due to an accumulation of excessive prostaglandin E-2 or its 19-hydroxy-prostaglandin E-2 in the old semen inventory ( http://www.actionlove.com/cases/case11407.htm  ).  19-hydroxy-prostaglandin E-2 is about 3-5 times more potent than prostaglandin E-2 in stimulating the tissue for pro-inflammatory factor Interleukin-8 (IL-8) release. This can explain why you are likely to experience pelvic congestion, ejaculation urgency, wet dream, and premature ejaculation after you retain our semen for a few days. IL-8 can alternate cellular DNA,  modulate neoplastic cell function and stimulate cancer (carcinomas) and tumor (tumorigenesis)  development and growth in the prostate and cervix. I believe it damages the erectile spongy tissue in the prostate, cervix, vagina and urethra.  This can explain excessive sex can cause vaginal enlargement and urethral pains and why the female cervix releasing excessive prostaglandin E-2 into the male penis during lovemaking induces premature ejaculation (and post-sex penile or prostate pain)-
( please read:
On the effect of the vaginal/cervical secretion on penile erection/ballooning and premature ejaculation. Why one tight vagina makes him erect harder and last longer for sexual orgasm , but the other tight one promotes his premature ejaculation?
==> http://www.actionlove.com/cases/case11032.htm ;
The cervical prostaglandin E-1 can erect the penis bigger and last longer; why the male PC exercises during sex and the dry vagina causes male premature ejaculation for no sexual orgasm
==> http://www.actionlove.com/cases/case12600.htm  or
On the effect of the vaginal/cervical secretion on penile erection/ballooning and premature ejaculation. Prostaglandin E-1 - the Solution for Vaginal tightness, penile ballooning and sexual orgasm
==> http://www.actionlove.com/cases/case11642.htm  )

On the other hand,  frequently blasting of the ejaculation duct by ejaculation, that is, over-ejaculation ( http://www.actionlove.com/extra/over.htm  and http://www.actionlove.com/extra/over2.htm ), will keep your PSA level high (your PSA level will stay high in 24-48 hours after each ejaculation !) and can cause local tissue/nervous damage, as well as burning the brain and nervous systems (including the dopamine, acetylcholine, serotonin and GABA nervous function to alternate the gene expression of the dopamine D1 and D2 receptors for an excessive dopamine-norepinephrine-epinephrine conversion),  to alternate the gene and enzyme expression,  suppress the COX-1 expression essential for the housekeeping (healing) prostaglandin E-1 synthesis in the local tissue in retaining the integrity/flexibility/elasticity of the local tissue/nerve/blood vessels/joint, and induce the COX-2 over-expression for the synthesis of prostaglandin E-2 responsible for pains, cramps, nervous disorder, blood vessel and tissue damage and inflammation, and, of course, dilation of the ejaculation duct resulting in premature ejaculation or semen leakage or emission during sexual arousal.  A high PSA and prostaglandin E-2 level may be correlated each other for over-ejaculators.
Weak erection is another factor for premature ejaculation. Weak erection forces you to contract the prostate and PC muscles to assist erection. the prostate/PC muscles contraction will trigger the testosterone-DHT conversion in the prostate and bulbourethral hormone receptors,  and then induce the COX-2 over-expression for inflammation of the prostate, bulbourethral glands and ejaculation duct for precum flooding followed by premature ejaculation. You should have a lot of precum discharge when you exercise your prostate/PC muscles. Precum contains prostaglandin E-1 and E-2. Although Prostaglandin E-1 enhances a short-term erection, but prostaglandin E-2 stimulates the urethral and prostate sympathetic nerves for a faster ejaculation. Prostaglandin E-2 suppresses neuroimmune in the local tissue and excite the urethral, prostate, vaginal/cervical cells for dilation of the orifice to allow semen to pass through (and labor for pregnant women or vaginal enlargement).  In severe cases, over-masturbators can experience a constant precum or semen leakage.  A urinary testing for the concentration of prostaglandin E-1 and E-2 level can disclose the precum or semen leakage problem.
A high level of norepinephrine and epinephrine in the prostate, semen vesicles and bulbourethral glands usually alternate the receptors' gene expression for an COX-2 over-expression and, thus, an excessive prostaglandin E-2 synthesis. In fact, in any tissue, a high level of norepinephrine and epinephrine will do the same thing, particularly in the neck, joints, low back, low abdomen, heart. kidneys, prostate, uterine-ligaments, urethra, testicles, penis and clitoris where people most likely experience pains and cramps.  A high level of norepinephrine and epinephrine in the bloodstream can promote the testosterone-DHT conversion for over-heating your blood and brain and preparing for Fight or Flight. When this happens in your brain and prostate, your erection will go limps and ejaculate in seconds. 
You need ViaPal-hGH-P and 5-HTP to help you out.
For penile enlargement, please read the links in -
Penile Enlargement and
Penile Enlargement Examples

PS: 1. Chronic medication drug use or street drug abuse (including alcohol and caffeine) can damage the brain/nervous, liver and kidney function and alternate the gene and enzyme expression.  Both cause premature ejaculation and erectile dysfunction. please read  http://www.actionlove.com/extra/streetdrugs.htmhttp://www.actionlove.com/extra/chem.htm , http://www.actionlove.com/extra/pe.htm ,and http://www.actionlove.com/extra/erection.htm 
2. COX-2 inhibitor drugs can inhibit the prostaglandin  E-2 and E-3 production, but also suppress the COX-1 expression in the prostaglandin E-1 synthesis.  Pregnant women should avoid a chronic use of COX-2 inhibitors since they will cause a deficiency of prostaglandin E-1 and E-2 in the cervix during labor. Prostaglandin E-2, particularly with a lack of prostaglandin E-1 produced by the local tissue, is responsible for vaginal enlargement (shrinkage/damage of the erectile spongy tissue) , penile/vaginal/urethral infection and abrasion, and intercourse pains/cramps.  Prostaglandin E-1 and E-3 are the most important hormones for the cardiovascular function, arterial dilation, nerve and tissue elasticity/flexibility,  and  cellular healing and repair.  Both prostaglandins are also the important elements of semen for the health of sex organs and the orgasmic responses during lovemaking.  A lack of prostaglandin E-1 and E-3 in the tissue can cause heart attack, stroke and kidney failure, in addition to pains or cramps and erectile dysfunction. That is, why you need Dr. Lin's natural Prostaglandin E-1 therapy, instead of taking COX-2 inhibitors for potential heart attack, unwanted bleeding, and cardiovascular/ liver/kidney disorder ( http://www.rxlist.com/cgi/generic/rofecox_ad.htmhttp://www.cnn.com/2004/HEALTH/09/30/vioxx.withdrawn.reut/index.html ) Please read some examples - 
After he spent all his money, why all his doctorS and all the prescription drugS can have never solved his non-bacterial prostatitis and prostate swelling with frequent urination, perineum heat/pains, and hair loss, leading to no more sexual orgasm - Here is Dr. Lin's cheap solution - The Natural Prostaglandin E-1 therapy.
==> http://www.actionlove.com/cases/case12346.htm  
He said ' i have been purchasing your products for about 4 months now for my wife. and they have helped a great deal!' for her Interstitial Cystitis (IC), fibromyalgia, migraine headaches, sleeping disorder, vaginismus (penetration/intercourse pains) and restoration of sexual orgasm - This serious case has been abandoned by the medical societies.
==> http://www.actionlove.com/cases/case12046.htm  
He said 'we all should recommend you for a noble prize in your field of study.' after experiencing the powerful Dr. Lin's Natural Prostaglandin E-1 therapy for prolonging his erection and sexual orgasm, increasing his semen production, darkening his hair, dropping his bad cholesterol level and blood pressure (with a high dose of Yohimbe in DopaFibra!? for bioplar and neuro disorder!), eliminating his body pains ...
==> http://www.actionlove.com/cases/case11983.htm  
She said ' I ordered your products Moodmax, Viagrowth-IV and 5htp for vaginal looseness right before Christmas.... I can say Your products really work. Thank! You have a customer' for Vaginal Tightness and more sexual orgasm! Again, the Dr. Lin's Natural Prostaglandin E-1 Therapy
==> http://www.actionlove.com/cases/case11964.htm 
Dr. Lin's Prostatitis solutions - the restoration of sexual orgasm with Natural Prostaglandin E-1 therapy.
==> http://www.actionlove.com/cases/case11924.htm  
He said ' dear dr lin WOW it worked!!!! i took borage oil 1 capsule a day,3 capsules fish oil and 6 capsules of flaxseed per day.....RESULT- longer sexual intercourse didnt cum as quick and a much harder penis that increased in length by 1 inch and a fatter girth my girl loved my 8inch cannon. i notice also after doing your breathing method i can shoot my big cannon for another round i also take your moodmax and viagrowth4 great stuff' for more sexual orgasm and having Merrier X'mas and happier holidays!
==> http://www.actionlove.com/cases/case11904.htm  
He said ' Hello, I have been taking the fish oils and the borage oils now for 4 weeks. I am also very pleased with your products and my hair as well as my wife's hair is turning dark again. My wife has been almost white since her late 30's This is nothing short of a miracle. Thank-you.' for more sexual orgasm! On Dr. Lin's Natural Prostaglandin E-1 therapeutic formula ==> http://www.actionlove.com/cases/case11805.htm   

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