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Based upon "Resonant Excitation Of Sexual Orgasms - Tao Of Love Coupling"
by Newman K. Lin, Ph.D., PE, a bridge between the Eastern Taoism Sexuality and the Western Engineering Science.==> [ORDERING THE BOOK]< =>[Why?]
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Warning: This is NOT an XXX Website, But we deal with Multiple, Sexual Orgasms and Impotence!
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Case Title:  Chronically masturbating twice a day lets her feel sexually unfulfilled, crave for more sex, and experience cramps in the low abdomen and back for sexual exhaustion symptoms, but no sexual orgasm. On the physiology and psychology of orgasm
Reader : 7/31/2004>
My husband and I had anal sex recently.We had done this before but it has been 2 years since the last time. I now want sex all the time. I cant stop thinking about it. I feel constant sexual stimulation. I try to not think about sex but my vagina keeps reminding me. I try to have sex so that the craving will go away but I just want more. I am starting to get cramping in my belly and back that goes away with rubbing or a hot bath.I now masturbate twice a day and my husband is tired of me wanting sex. I have never had this happen to me. Is this normal?
Dr. Lin: 7/31/2004>It seems your clitoris, G-spot, vulva and urethral/vaginal spongy tissue are inflammatorily swelling all the time, partially due to sympathetic erectile mechanism (the binding of norepinephrine and epinephrine into the beta receptors) and partially due to tissue abrasion that activates an over-expression of enzyme COX-2 and an excessive histamine release for inflammatory itching.
You need a real orgasm (uterine contraction orgasm) to reset the erecting spongy tissue back to the flaccid state, and suppress the COX-2 and histamine expression as well.
Chronic over-masturbation won't give you a real orgasm, but constantly burn your acetylcholine and serotonin and trigger your dopamine-norepinephrine-epinephrine conversion without stimulating your pituitary gland to release sufficient oxytocin for the initiation of uterine contraction and the emotional binding with your partner and to flood enough prolactin to shut down your libido and to switch the binding of norepinephrine and epinephrine from the sympathetic nervous beta receptors to alpha receptors, where the switching of the norepinephrine/epinephrine binding from the beta to alpha receptors will induce the sympathetic nervous acting potential (pulsing voltage) to pace a sequence of uterine orgasm contraction and then return your erecting clitoris, g-spot, vulva, urethral/vaginal spongy tissue back to the flaccid state.
A high level of norepinephrine and epinephrine in the tissue will block the prostaglandin E-1 synthesis if your acetylcholine /parasympathetic nervous function is weak or the action of the enzyme COX-1 on the Omega-6 fatty acid is weak. Instead, you may get an over-production of the harmful prostaglandin E-2 for pain and inflammation and an over-release of histamine for itching or allergy.
When you maintain a high norepinephrine and epinephrine level in the bloodstream by masturbation twice a day and let them be bonded into the beta receptors for a constant dilation of your arteries and erectile tissue without sufficient relaxin and elastin prostaglandin E-1, you ask for pains or cramps (the most obvious, sexual exhaustion symptoms)
As a result of the over-stimulation of the tissue and an excessive binding of norepinephrine and epinephrine into the beta receptors, you may get an over-inflammatory vulva and vagina due to an over-expression of enzyme COX-2 and an excessive production of prostaglandin E-2 and histamine down there.

OK. let me outline the physiology and psychology of orgasm as follows:
Sexual arousal triggers dopamine-norepinephrine-epinephrine conversion in the hypothalamus/pituitary gland where an increase of norepinephrine stimulates the pituitary to release oxytocin and prolactin. If prolactin increases too fast and faster enough to switch the binding of norepinephrine and epinephrine from the beta to alpha receptors for the sympathetic nervous Fight or Flight action, you will lose your sexual desire and erection (going limp!), that is the sympathetic "Flight" response, or experience premature orgasm or premature ejaculation, that is the sympathetic Fight response, during sex. 
When you are approaching an orgasm, your hypothalamus and pituitary gland will sharply shoot up your norepinephrine, epinephrine, prolactin and oxytocin production at the same time.  Oxytocin in the bloodstream is to initiate the uterine contraction; norepinephrine and epinephrine triggers the sympathetic nervous acting potential to pace the uterine orgasm contraction (actually the entire body contraction when you experience the Level-7 eruptive orgasm, leading to little death, headaches, seizure, body shaking or cramps!) when prolactin dynamically switches their binding from the beta to alpha receptors, back and forth, in synchronizing the uterine-contraction feedback pulses to the hypothalamus and pituitary gland at a rate of 0.8 second; the uterine orgasmic contraction produces 0.8-second orgasmic waves running up to the heart, lungs and brain via the acupuncture energy channel Conceptive Vessel and the vagus nerve (parasympathetic) along the central front body ( http://actionlove.com/image/wavepath.jpg;  note that some energy can go into the spine via the S2-S4 and L1/L2 and Governing Vessel since the clitoris and uterus contain the vagus/S2-S4/L1-L2 nerves); once most of norepinephrine and epinephrine are bonded into the alpha receptors, your clitoris, vulva, G-spot and urethral/vaginal tissue return to the flaccid state; then, prolactin shut down your libido and oxytocin let you feel be sexually satisfied and psychologically bonded to your partner.
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