High-frequency sex results in premature ejaculation and impotency

Warning (Another lesson of sexual exhaustion symptom): High-frequency sex results in premature ejaculation and impotency . If your penis goes limp inside her vagina, the vaginal fluid with a high level of prostaglandin-E2 will be sucked into your urethra and prostate to sensitize the internal nerves for instantaneous ejaculation. You must avoid this nervous chemical stimulation.

Here we go again!


Date: Tuesday, November 21, 2017 at 14:01:10

Age: 38

Country: germany

Problems: Dear Dr.Lin,

Seven years ago I was your customer dealing with PE, having for 6 months ViaPal-hGH-J and PinealTonin. All went really good, pills together with anal breathing kept me for 30 minutes of clean sex, easily. My partner had 2-3 easy orgasms for warming up and almost every time the 3 point big bang in the end. 🙂
About one year ago I have started having multiple partners beside my wife, having sex almost daily. At some point I used also some erection pills, became tricky to power it up every day but my brain was and still is asking for more. Not watching porn or any other visual stimulants.
All together, brought my PE back that now I have to go second time ejaculating also, which makes the things even worse. For now I don’t have any signs of sexual exhaustion.

Bottom line: can you please recommend something for PE and for general sexual condition as for someone of 38 years old?
Currently I have 3 partners that I intend to keep and have sex second day, at least. 🙂

Thank you and looking forward to your answer.

Answer from Dr. Lin:
You got sexual exhaustion symptoms, as described in http://www.actionlove.com/extra/ses.htm

High-frequency ejaculation causes the excessive-norepinphrine-induced prostaglandin E2 synthesis in the seminal vesicles and prostate, and weak erection due to arterial constriction by the excessive prolactin level in blood stream, as well as the inflammation and abrasion of the prostate ejaculation duct and the urethra. The chemically and mechanically damaged prostate and urethra become very sensitive to the prostaglandin E2 encriched pre-ejaculation fluid and the vaginal fluid (which also contains a high level of prostaglandin E2 for the sperm survival and fertility.)

You have to reduce your ejaculation frequency to once every 2-3 days to give your prostate a break, and your brain’s dopamine nervous system must get fully recharged and recovered before another run of sex.

You can take the same products, ViaPal-hGH-J (3-015) and PinealTonin (2-002), with Omega-3 Fish Oil (2-005) and Vitamins D(2-004) and E, for recovery –

No automatic alt text available.

Lotus Siiting-3Point Excitation

The 3-point Excitation Position for Big-bang orgasm! The inter-body Qi Circulation can be done by the vagus nervous stimulation between the glans and
cervix/Epicenter, and between the male pubis and female pubis/cliroris; with the mutual deep toungue
peneration kissing that activates the hypoglossal nerve CN-XII and the trigeminal nerve CN-V.

Incorporation of the Kunderlini Yoga Root Chakra firing circuit into Aquila Anal-Breathing, Vagus-Nerve-Stimulation (VNS) QiGong (天鷹牛郎迷走功)

Incorporation of the Kundalini Yoga Root Chakra firing circuit into Aquila Anal-Breathing, Vagus-Nerve-Stimulation (VNS) QiGong (天鷹牛郎迷走功) 

Traditionally, Qigong focuses on the stimulation of the vagus nerve around the bladder (pelvic cavity) and the low section of the intestines inside the low abdominal cavity; Anal Breathing is to use the gluteus muscle (contraction against the sacral/tailbone nerve (parasympathetic) to counteract the sympathetic nervous response to sexual stimulation, and to  interfere with the prostate-L1/L2 ejaculation control circuit in the lumbar spine, where the horse-stance posture pre-stresses the L1/L2 sensory nerves in the pubis, pelvic floor and thighs.

Since you pre-stretch the PC and pelvic floor muscle ( it is like a pre-stressed bridge) in the horse-instance posture, sinking your butts more is to stress it more, Therefore,  all you need is let the muscles return to their original tension/stress in the house-stance posture when you move your butts upward. To stimulate the tailbone nerves (S1-S5 and Co), contract the glutes muscle against the anal/tailbone muscle, as a principle of the anal breathing qigong.

The Kundalini Yoga wants you to contract the PC/pelvic floor muscle to fire up the Root Chakra. Since the horse-stance posture pre-stresses (pre-stretches) the PC/pelvic floor muscle, we have found that under a wide-open horse stance, contracting the PC/pelvic floor muscles won’t squeeze the prostate and seminal vesicles. This allows the Kundalini Yoga’s Root Chakra firing stimulation to be incorporated into the movements.

You have to perform about 500 squat exercises twice a day.

Aquila Qigong squat exercises allow you to stretch the pelvic floor muscle while sinking your butts downward with exerting a light pressure toward your bladder (low DanTian),
When you move your butts or upperbody upward, you can contract your entire pelvic floor muscles and gluteus muscles against your tailbone.
There are many Aquali Qigong movements in the video which can incorporate the anal breathing, beside the Swimming Frog Squat. https://youtu.be/Id7tGe-kR5g
They are
3. Swimming Frog Squat
5. Penguin Squat
8. Cowboy Cyclic Lassoing
9. Cowgirl Wild Ride
10. Garuda Pray
11. Hugging a Bear
16. Horse Rearing
17. Duck Tornado Dance
19. Gibbon Swing
20. Giraffe Plucking
21. Freedom Flight
22. Volcano Qi Eruption

Squirt Orgasm vs. Rolling Eye Orgasm

Squirt Orgasm vs. Rolling Eye Orgasm

Reader question on 6/29/2017:

Hi Dr. Lin, Which one is better, Squirt orgasm or Rolling Eye orgasm? Based on the answer above, what’s top 5 best position to make it happen (Let’s say foreplay are already very good)? Thankyou…

Dr. Lin’s Answer on 6/30/2017:

Depends if squirt orgasm discharges urine from the urethral tract.  If the female ejaculation is urine, it is a urethral nervous stress incontinence; if not, it is OK.  Ejaculating hot fluid from the urethra or vagina  will give women orgasmic sensation.  Orgasm or not, depends on the brain’s dopamine nervous discharge that stimulates the pituitary oxytocin and prolactin release in the dopamine-hypothalamus-pituitary axis.  Squirt orgasm is usually induced by the clitoral or/and G-spot stimulation via the sympathetic nervous stimulation with a minor vagus nerve response (the vagus fiber terminated at the glans clitoris.)

Generally, the uterus and vaginal (and urethral) smoothing muscles (spongy tissues) store body fluid.  During sexual arousal, a large amount of body fluid flows to the uterine and vaginal smooth muscle. For women who have small lymphatic vessels (the fluid storage duct system) to store fluid, clitoral and G-spot stimulation can over-pressurize the duct system to ejaculate, even without an orgasm.  C-section turn some of the uterine smooth muscle into collagen scar,  let the uterus lost the capacity to store the body fluid, and redirect more fluid into the vagina-urethral smooth muscles.  During sexual arousal, the pituitary gland releases oxytocin to open and dilate the lymphatic ducts and the arteries in the undamaged parts of the uterus to overload the damaged uterus for female ejaculationfrom the uterus into the vagina.

Actually, any limitation of the uterine fluid storage will result in overloading the duct system in the vagina-urethral smooth muscle for squirting from the urethra or vagina during sexual arousal, even without orgasm. No all squirting is a result of orgasmic contraction. Squirting by overloading the lymphatic duct system is like an explosive urination forced by an overfilled bladder.  Have you ever experienced with an overfilled bladder before? You should get a urinary urgency from that.

(This work is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person’s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code.

Credit: Wikimedia Commons https://commons.wikimedia.org/wiki/File:2202_Lymphatic_Capillaries_big.png

Rolling Eye orgasm is better and known as “Little Death orgasm,” but it requires deep vaginal/cervix vagus nerve stimulation (the Root Chakra stimulation for kundalini energy, or the low DanDien stimulation in Taoism Qi theory. ) The Low Dantien’s tissue is smooth muscle and its nerve consists of the vagus (parasympathetic) and sympathetic fiber. Your need at a 6-inch penis (at least) with a solid erection to reach the deep vaginal ending (I called Epicenter for the Low DanDien) where the vagina/cervix/uterus/bladder’s vagus nerve are convergent together. As long as you can reach this point and stimulate it, it doesn’t matter which love positions. A penis longer than 8 inches long will allow the glans penis to be locked or sucked up by the deep vaginal ending smooth muscle in any love positions to achieve vagus nerve stimulation from Low DanTien; otherwise, the 3-point excitation love position (or the lotus-sitting position with the female horizontal thrusting movement ) with a 6-7 inch vaginal penetration is the only way to stimulate the vagus nerve in raising the Kundalini energy (Qi) from the Root Chakra.  http://www.actionlove.com/WordPress/2015/02/17/electrifying-orgasm/ 

The low DanTian (the Center of the Lotus Flower) is about 6 inches from the vaginal orifice.

Lotus Siiting-3Point Excitation

The inter-body Qi Circulation can be done by the vagus nervous stimulation between the glans and
cervix/Epicenter, and between the male pubis and female pubis/cliroris; with the mutual deep tongue
penetration kissing that activates the hypoglossal nerve CN-XII and the trigeminal nerve CN-V.

Aquila Anal Breathing, VNS Qigong energized his body all day long and gave him a deep night sleep

AquilaQigong-readerCommentsRef: Aquila Anal Breathing, VNS Qigong  – https://www.youtube.com/watch?v=Id7tGe-kR5g&nohtml5
On 4/7/2016 6:56 AM, hxxxxx axxxx wrote:

Hello, Lin. I am so thankful to you for putting such powerful information out for free. I have only done your exercises once and I have been sleeping properly and feeling energetic all day.

I have one confusion though. When you breathe into the pelivs, does your anus sphincter muscle push out?



Dr. Lin’s Answer:

You don’t have to do anything on your anus sphincter muscle until your contract your gluteus muscle when bending your upper body backward.
Here is my answer to other reader in https://www.youtube.com/watch?v=Wlow3ukCud4&list=PL7vDuc1LOT4uq9sFAGW6GkkfweHLzdx-c&nohtml5 :

The simple way to force the Qi into your genitals or pelvic cavity is: with horse-riding stance, inhale with the low abdominal – pelvic expansion, bend your upper body forward so that your shoulder and head are below the pelvic area (or the Low DanTian); then further lower your horse-riding stance to stretch the pelvic floor muscle to an extreme (Qi will sink into the pelvic floor and testicles); at this moment,  compress the PC muscle as as hard as your can to direct Qi across the anus and to enter the tailbone; finally, raise your upper body and return your torso vertically back to the original horse-riding stance position;  followed by pushing your pelvic forward, bending your upper body backward, and at the same time, contracting  your gluteus muscles against your tailbone to force Qi to raise up along the spine while slowly and gradually raising up from your horse-riding stance. Some Aquila Qigong movements in https://www.youtube.com/watch?v=Id7tGe-kR5g&nohtml5 just use this approach to circulate QI and to generate nervous pulses in the vagus and autonomic neurons in the pelvic cavity.

Aquila Anal-Breathing, Vagus-Nerve-Stimulation (VNS) QiGong (天鷹牛郎迷走功) Version 2.0

Aquila Anal-Breathing, Vagus-Nerve-Stimulation (VNS) QiGong
Version 2.0
Newman Kunti Lin, Ph.D., PE.
Copyright © 2016

Aquila Qigong is to emulate animal
movements for stimulating the central
nervous system via the pelvic
vagus and sacral parasympathetic
neurons with a minor stimulation
on the sympathetic nervous system.
It fires up the bioelectric energy
from the bottom (the pelvic cavity
and floor), also known as the
Kundalini Root Chakra.

Dr.Lin’s Aquila Anal-Breathing,Vagus-
Nerve-Stimulation(VNS)Qigong begins
with following love story:

In an oriental legend, Aquila’s Altair (the
Cowboy 牛郎) and Lyra’s Vega (the
Weaver Girl 織 女) had been madly
in love since the beginning of the
heaven; and, finally, their true love
had convinced the God of the Heaven
to allow them to get married as human
beings on the earth.

The God asked Aquila, the eagle, to carry
them down to the earth along the Milky Way
in the evening of July 7 (in the lunar
calender) so that they could enjoy love
and passion forever. The God also turned
the Milky Way into the dragon which actually
helped Aquila instruct the love couple to
initiate and to strengthen their reproduction
function with the cycling stretching exercises
of the pelvic floor bones and muscles by
emulating the animal movements.

These exercises were formulated to boost
the bioelectric nervous activity (known
as “Qi” ) and the blood circulation in
the genital area for “love longer” and
“last longer.”
The exercises, having the similar pelvic
movement as the Taoist Qigong such as
Wudang Taiyi Gong(武當太乙功) and
Crouch-step BaguaZhang Gong(蹲伏八卦掌
功), excite the first acupuncture point of
both the Governing Vessel and Conception
Vessel,Cháng Qiáng 長強 (in the midway
between tip of coccyx and anus, requiring
deep stimulation to reach the nerve in the
smooth muscle) and Huì Yīn會陰 (at the
center of the perineum; about 1-2
inches deep to reach the nerve in
the smooth muscle – the same depth
as the female G-spot and male
bulbourethral glands), respectively,
which are also known as the Kundalini
Root Chakra; induce the pelvic blood
flow; generate bioelectricity
via the cycling biomass (bone and
muscle) stretching and contraction
to charge the local nerves; elevate
the androgen hormones and human growth
hormone production in about 30 minutes.
With this practice, the Weaver Girl
becomes a sexual awakening cowgirl.
Here, the bioelectric energy in the Kundalini
Root Chakra is activated by the
parasympathetic and vagus nerve with
a minor sympathetic nervous stimulation
(lumbar L1-L5 and thoracic T10-T12.)
The nervous pathway is from the
pelvic parasympathetic (Sacral S2-S4)
and vagus neurons to the dopamine neuron
in the thalamus-hypothalamus-pituitary axis.
In practice, the pelvic floor muscle and
nerve are pre-stretched with the horse-
stance posture to begin with. Sink the
torso (move the torso vertical downward )
will further expand the pelvic muscle and
pubic bone to allow the cycling muscular
contraction without over-stimulating the
prostate and bulbourethral gland and
inducing leakage of pre-ejaculation or
seminal fluid. To fire up the vagus-
pituitary pathway from the low-abdominal
and pelvic cavity, as Dantian, use the
abdominal-pelvic muscles to inhale while
moving torso downward, and bend the
upper body forward to compress the
abdominal-pelvic cavity. This movement
will exert a pressure on the bladder
and stretch the joint muscle of the
colon and rectum. It is also known
as “sink Qi into Dantian”.

Moving the pelvis forward or/and
bending the upper body backward will
naturally force the gluteus muscle to
contract against the tailbone muscle,
like pushing the tailbone-anal muscle
toward the spine without contracting
the pubococcygeus (PC) muscle.
This is known as Anal Breathing.

Rotating the pelvis horizontally or
vertically will produce a powerful
Qi generation and a good blood
circulation from the pelvic cavity.
Aquila Anal Breathing, VNS Qigong
combines pelvic rotation and upper
body bending to maximize the biomass
bioelectricity (Qi) generation and
neuro-and muscular endocrine function.

Outline of Aquila Qigong Movements:

1. Aquila Descending From Galaxy 起式下凡
2. Riding a Swimming Dragon 醍鷹游龍
3. Swimming Frog Squat 蛙泳前伏
4. Monkey Crouch 靈猴伏歩
5. Penguin Squat 企鵝鷹形
6. Aquila-Tiger Transformation 神鷹虎形
7. Leopard in Aquila Shadow 鷹影豹形
8. Cowboy Cyclic Lassoing 牛郎捕牛
9. Cowgirl Wild Ride 織女野騎
10. Garuda Pray 著地祈禱
11. Hugging a Bear 馬歩熊抱
12.. Back kick and Rotation 後踢旋身
13. Peacock Spreading 孔雀散花
14. Eagle Attack 前踢攻擊
15. Eel Attack in Aquila Shadow 鷹引電鰻
16. Horse Rearing 鷹泳立馬
17. Duck Tornado Dance 鴨尾旋風
18. Rotating a Tree 旋身轉樹
19. Gibbon Swing 猿臂後旋
20. Giraffe Plucking 春鹿摘星
21. Freedom Flight 飛鷹在天
22. Volcano Qi Eruption 一氣沖天
23. Return to Galaxy 囘歸天庭

How to Practice Anal Breathing Qigong with PC muscle “contraction” without inducing pre-ejaculation fluid leakage

Student’s Question:

Hello, Dr. Lin. Dr. I want to ask how it feels to apply pressure to the bladder? I haven’t been able to separate my PC muscles and for that I want to know whether I’m applying the pressure to the bladder right. If I want to pee and I apply pressure to the bladder, would it stop my pee?

Dr. Lin’s Answer:
Your scrotum will become loosened and move lower when you sink Qi into your pelvic cavity (against bladder).
Inhale; sink Qi into the pelvic cavity in the horse-riding stance; gradually sink your torso vertically.
Basically, you stretch your pelvic muscle (including the PC muscle, of course)  with the horse-riding stance,  and then you can start periodically contract your PC muscle when you lower down your torso and bend your upper body forward with moving your butts backward to balance your bending horse-riding stance.  Finally, return you upper body upright and backward  to contract your gluteal muscles against your tailbone and anal muscle while moving your pubic/pelvic bone forward.  You can relax your breathing when returning your body to the normal horse-riding stance.
In this way, the PC muscle contraction won’t affect its internal supporting organs such as the prostate and bulbourethral glans.
Release the PC muscle when your torso moves up.
This is the best way to combine both Qigong Anal Breathing and PC muscle “contraction”
You can stop urinary flow by contracting the gluteal muscles against the tailbone/anal muscle even if you apply a pressure to the bladder. Qigong with PC muscle contraction

How to perform Vagus Nerve Stimulation (VNS) from your bottom (pelvic floor) with VIP Cream , of course, without an electronic pulse generator?

How to perform Vagus Nerve Stimulation (VNS)  from your bottom (pelvic floor) with VIP Cream , of course, without an electronic pulse generator?

VIP Cream                                 http://linstitute.apollohosting.com/store/page15.html

Believe it or not: stimulating your bottom can turn on your top, that is your brain, via the nervous freeway – the vagus nerve.  In Traditional Chinese Medicine, it is a stimulation of huì yīn會陰 and cháng qiáng 長強from inside. You don’t need a acupuncture needle either!

Vagus Nerve Stimulation can lighten up the central dopaminergic function on the limbic system and the dopamine rewarding circuit – https://en.wikipedia.org/wiki/Limbic_system#/media/File:Blausen_0614_LimbicSystem.png and https://upload.wikimedia.org/wikipedia/commons/9/9d/Mesolimbic_pathway.svgLimbicSystemDoapmineRewardSystemVagus-spinalNerves4The brain’s reward system mainly includes glutamatergic interneurons, GABAergic medium spiny neurons, dopaminergic projection neurons, and orexinergic projection neurons, associated with eating, drinking and sex.  VNS affects most of the neurons in the brain’s rewarding system.  The dopaminergic neurons and glutaminergic interneurons are responsible for instantaneous responses to any physical and psychological stimulations,  particularly, in work place, dangerous encounters, and bedroom (love encounters), as described in http://www.ncbi.nlm.nih.gov/pubmed/16963001

There are 4 major dopaminergic pathways in the human’s brain to be improved by VNS:

  1. The mesolimbic pathway, a dopaminergic pathway,  plays
    a central role in neurobiology of addiction, schizophrenia, and depression.
  2. The tuberoinfundibular pathway is  a population of dopamine
    neurons regulate the secretion of prolactin from the anterior
    pituitary gland.
  3. The nigrostriatal pathway is a dopaminergic pathway that
    connects the substantia nigra with the dorsal striatum.
  4. The mesocortical pathway, a dopaminergic pathway in the
    frontal lobe( located at the front of the brainin) is essential
    to the normal cognitive function of the dorsolateral
    prefrontal cortex (part of the frontal lobe), and involved in
    cognitive control, motivation, and emotional response

VNS has been used to improve the following conditions:

  • Alzheimer’s disease
  • Anti-inflammation
  • Anxiety disorders
  • Alcohol addiction
  • Atrial fibrillation
  • Autism
  • Bulimia nervosa
  • Burn-induced organ dysfunction
  • Chronic heart failure
  • Chronic intractable hiccups
  • Comorbid personality disorders
  • Coronary artery disease
  • Digestive function
  • Dravet syndrome
  • Drop-attacks
  • Erectile dysfunction
  • Fibromyalgia
  • Heatstroke
  • Heroin seeking behavior
  • Intestinal epithelial barrier breakdown
  • Immunity
  • Lennox-Gastaut syndrome
  • Low libido
  • Memory
  •  Migraines
  • Mood disorders in elderly population
  • Multiple sclerosis
  • Myocarditis
  • Obsessive compulsive disorder
  • Obesity
  • Parkison’s syndromes
  • Peripheral arterial occlusion disease
  • Postoperative cognitive dysfunction in elderly patients
  • Rasmussen’s encephalitis
  • Severe mental diseases
  • Sepsis
  • Sexual disorders
  • Spinal trigeminal neuronal
  • Tinnitus
  • Transient focal cerebral ischemia
  • Trauma-hemorrhagic shock
  • Traumatic brain injury
  • Vaginal-Cervical self-stimulation in women with complete spinal cord injury
  • Vegetative States After Traumatic Brain Injury
  • Visceral pain-related affective memory

Here, we use VNS to enhance the erectile function and the orgasmic contraction of the smooth muscle inside the pelvic organs or outside such as the clitoris and  the penis. Apply VIP cream to massage the clitoris, the vagina, the anus and the penis for 5-10 minutes couple times a day. Or apply it to the vulva and the vagina or the penis during copulation.

About 0.5-1.0 inches Inside the vagina or anal cavity, the skeletal muscle and the smooth muscle meet together. In the vagina canal, the meeting (cross-talk) zone is called the G-spot,  and in the anal canal, it is called Dantate Line with a transition in Anal Columns of Morgagni.   In side the vaginal canal, the vagus and autonomic nerves are inside the epithelium of  the smooth muscle. In the anal canal,  if you massage the front side of the anal transition zone against the acupuncture point huì yīn會陰, you will directly stimulate the vagus nerve via the adjacent reproduction organs as well as the inferior hypogastric nerves (mainly from the spinal nerves L1-L3, lumbar sympathetic nervous plexus) , and the splanchnic nerves (sacral parasympathetic nervous plexus) and the pudental nerves (the sacral somatic nervous plexus for skeletal pelvic muscle around the anus, testicle suspension ligament, and vagina along with the sympathetic fibers to the smooth muscle in the testicles, clitoris and penis ) that  originates from the lumbo-sacral plexus (lumbar L4 and sacral S2-S4).  Massaging the back of the anus toward the acupuncture point  cháng qiáng 長強 stimulates the splanchnic and pudental nerves that arise from sacral spinal nerves S2-S4.  The stimulation of the autonomic nerves (parasympathetic nerves from sacral sections S2-S4, and sympathetic nerves from lumbar discs L1-L3)  in the epithelium of the anal canal transitions,  from colonic and rectal simple columnar epithelium to stratified squamous epithelium,  can also release prostaglandins and nitric oxide to excite the vagal sensory nerve in the lower section of colon, known as the sigmoid colon transitions into the rectumA deeper stimulation of the anus-rectum can directly activate the vagus nerve and inferior hypogastric nerve in the smooth muscle of  the sigmoid colon transitions. However, the direct stimulation can damage the rectum lining.  Noticeably, the average length of the human rectum may range between 10 and 15 cm, about the averaged penis length.  For this reason, anal sex lets some women experience powerful orgasms as a result of the direct vagus nerve stimulation on the sigmoid colon transition.  A gentle,  shallow anal stimulation relies on the cros-stalk  among prostaglandins, nitric oxide, neurohormones and nerves to achieve VNS in the internal genital organs or  the  sigmoid colon transition.

The vagus nerve, pelvic/sacral splanchnic nerves,  and lumbar inferior hypogastric nerves are activated by the transient receptor potential channels which are mechano-and chemo-sensors on visceral afferents (sensory neurons.) Therefor, it is not necessary to exert a heavy stimulation for turn on the delicate tissues.(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789877/;
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008997/ )

Massaging both right and left side of the anus stimulates the sacral pudental nerve, The pudental nerve located the sacrospinous ligament, near the tailbone and extends from the sacral plexus, through the pudendal canal, into the genital regions, the perineum, and the gluteal area.  Although the pudental nerve mainly carry the somatic motor and sensory fibers to the skeletal muscle around the anus and the entire pelvic floor, but it also supplies the sympathetic fibers for penile and clitoral erection and ejaculation or orgasm contraction. It is responsible for bowel and urinary continence control and genital sensation.  http://www.ncbi.nlm.nih.gov/pubmed/12951671 Pelvic Splanchic Nerve and Pudental NervePudendal nerve, course and branches

You can stimulate the somatic, vagus and automatic nerves at the same time by massaging the smooth muscle or the transition zone with VIP Cream. Please be aware that directly massaging the smooth muscle can damage it. It is preferred to do it on the transition zone where the mixed tissue is stronger and stiffer than the pure smooth muscle.female genital-anusAnanl ColumnSuccess requires responsiveness, endurance, and persistence with a short recovery time.  VNS can help you become very responsive. You need it in the first place. To extend the VNS effects on  your endurance and persistence, you need androgen hormones, such as DHEA, testosterone and DHT,  to continuously burn. But, How?; Why?
The gonadal / androgen hormones are essential for physical and mental strength, but they exert primarily slow, genomically mediated effects. In most of the typical working places such as offices, fields, and/or even bedroom, you may need fast responsiveness and prolonged endurance to achieve your goal and to complete your task. A faster responsiveness with calmness can only be achieved by nervous action from the dopamine, glutamate and serotonin system, with a good blood circulation, provided by the arterial relaxation and dilation from the NO (nitric oxide)- cGMP (cyclic guanosine 3′,5′-monophosphate) signaling pathway, and by stress reduction. 
A good blood circulation will continuously supply gonadal hormones to the working muscles (including smooth muscles) and joints to support the physical and mental endurance for your act.
The endurance also requires flexibility of muscles joints without worrying about inflammatory pains. We have found a high dose of Omega-3 Fish Oil (about 3000 mg omega-3 fatty acids) with 81 mg Aspirin is very helpful.
Overall, our products ViaGrowth-IV, MoodMax, DopaFibra, ArgiNOx and Omega-3 Fish Oil can help you to have better responsiveness and endurance and faster recovery. 
By the way, our stress reduction formulas are PinealTonin or 5-HTP, as described in
Stress reduction can indirectly improve your endurance and directly reduce performance anxiety.

Dopamine vs Male HormonesSex benefit women in many ways which include VNS inside the vagina; on the cervix, uterus and bladder; and on the clitoral shaft and glans, the bulbocavernosus, and the
ischiocavernosus that contain erectile smooth muscle and are
innervated by the the vagus nerves and parasympathetic
nervous from S2-S4 and sympathetic nerves from L1-L-3.
1. Larrazolo-López A1, Kendrick KM, Aburto-Arciniega M, Arriaga-Avila V, Morimoto S, Frias M, and Guevara-Guzmán R., ” Vaginocervical stimulation enhances social recognition memory in rats via oxytocin release in the olfactory bulb.”  Neuroscience. 2008 Mar 27;152(3):585-93. doi: 10.1016/j.neuroscience.2008.01.024. Epub 2008 Jan 25. http://www.ncbi.nlm.nih.gov/pubmed/18304743;
2. Komisaruk BR,  and Sansone G. ” Neural pathways mediating vaginal function: the vagus nerves and spinal cord oxytocin.” Scand J Psychol. 2003 Jul;44(3):241-50. http://www.ncbi.nlm.nih.gov/pubmed/12914587
3. Komisaruk BR, Bianca R, Sansone G, Gómez LE, Cueva-Rolón R, Beyer C, and Whipple B., “Brain-mediated responses to vaginocervical stimulation in spinal cord-transected rats: role of the vagus nerves.” Brain Res. 1996 Feb 5;708(1-2):128-34. http://www.ncbi.nlm.nih.gov/pubmed/8720868 )

Coitus with a hard, hot penis can provide a powerful blending stimulation on the nerves in the cervix, the uterus, and the bladder internally; and on  the clitoral shaft and glans, the bulbocavernosus, and the  ischiocavernosus, externally when using the 3-point excitation love position (also in http://www.actionlove.com/WordPress/2014/08/29/aquali-anal-breathing-qigong-induced-erection/ ) or the screwing method (by him) (or by her.)


For men, the VNS stimulation during sex is limited to the penile shaft and glans,  the ischiocavernosus around the penile root inside the pelvic floor,  and the prostate. MalePelvic4

Beside coitus , VNS can be achieved by massaging the acupuncture points, huì yīn會陰 and cháng qiáng 長強 with an insertion of a 0.5-inches finger section into the anus or/and into the vagina (for women),  with VIP Cream.

By the way, Anal Breathing QiGong exercises (also in http://www.actionlove.com/WordPress/2014/11/26/somatic-nervous-function-in-qigong-qi-circulation-how-do-you-circulate-qi/ ) can help you directly stretch the bulbocavernosus (for women) and the ischiocavernosus (for both men and women.).  I want you to know Anal Breathing Sexual Qigong Exercises directly link genital organs to the brain, particularly the central dopamine (DA), noradrenaline (NE), and serotonin (5-HT) nervous systems (review papers given in www.mdpi.com/2076-3425/3/1/39/pdf and http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507374/pdf/jcn-11-212.pdf ) , and the endocrine function for hGH, DHEA, testosterone and DHT production.

Special Reference for  the Somato-vagal, Somato-parasympathetic, and Samto-sympathetic Nervous Cross-talk: the stimulation of the pelvic muscles simultaneously activate somato-parasympathetic, somato-vagal and somato-sympathetic reflex arcs (nervous cross-talk in the inter-neurons). ( References:  1. Terui N, and Koizumi K.,  “Responses of cardiac vagus and sympathetic nerves to excitation of somatic and visceral nerves.” J Auton Nerv Syst. 1984 Apr;10(2):73-91. http://www.ncbi.nlm.nih.gov/pubmed/6747203.;  2. Sato, A., “Neural mechanisms of autonomic responses elicited by somatic sensory stimulation. Neurosci Behav Physiol. 1997 Sep-Oct;27(5):610-21. http://www.ncbi.nlm.nih.gov/pubmed/9353786; 3. Kimura A, and Sato A., “Somatic regulation of autonomic functions in anesthetized animals–neural mechanisms of physical therapy including acupuncture.” Jpn J Vet Res. 1997 Nov;45(3):137-45. http://www.ncbi.nlm.nih.gov/pubmed/9433014; 4.  Loaiza LA, Yamaguchi S, Ito M, and Ohshima N., “Electro-acupuncture stimulation to muscle afferents in anesthetized rats modulates the blood flow to the knee joint through autonomic reflexes and nitric oxide. Auton Neurosci. 2002 May 31;97(2):103-9. http://www.ncbi.nlm.nih.gov/pubmed/12132642; 5. Li, J, and Mitchell JH., “Role of NO in modulating neuronal activity in superficial dorsal horn of spinal cord during exercise pressor reflex.” Am J Physiol Heart Circ Physiol. 2002 Sep;283(3):H1012-8. http://ajpheart.physiology.org/content/ajpheart/283/3/H1012.full.pdf; 6. Smith SA, Mitchell JH, and Garry MG., “The mammalian exercise pressor reflex in health and disease.” Exp Physiol. 2006 Jan;91(1):89-102. Epub 2005 Nov 10. http://onlinelibrary.wiley.com/doi/10.1113/expphysiol.2005.032367/full ; 7. Gallagher KM, Fadel PJ, Smith SA, Strømstad M, Ide K, Secher NH, and Raven PB., “The interaction of central command and the exercise pressor reflex in mediating baroreflex resetting during exercise in humans.” Exp Physiol. 2006 Jan;91(1):79-87. Epub 2005 Nov 1. http://onlinelibrary.wiley.com/doi/10.1113/expphysiol.2005.032110/full ; 8. Fadel PJ, and Raven PB.,”Human investigations into the arterial and cardiopulmonary baroreflexes during exercise.” Exp Physiol. 2012 Jan;97(1):39-50. doi: 10.1113/expphysiol.2011.057554. Epub 2011 Oct 14. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253263/pdf/nihms332393.pdf )


  1. http://www.ncbi.nlm.nih.gov/pubmed/26433214
  2. Pavlov, V.A.; Tracey, K.J. “The vagus nerve and the inflammatory reflex–linking immunity and metabolism.” Nat Rev Endocrinol. 2012 Dec;8(12):743-54. doi: 10.1038/nrendo.2012.189.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082307/
  3. http://www.nature.com/ncomms/2015/150630/ncomms8490/full/ncomms8490.html
  4. https://www.gdsm.espci.fr/sites/www.gdsm.espci.fr/IMG/pdf/PlacaisPreat2012.pdf
  5. http://www.ncbi.nlm.nih.gov/pubmed/22608184
  6. http://www.ncbi.nlm.nih.gov/pubmed/12922929
  7. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473270/
  8. http://www.ncbi.nlm.nih.gov/pubmed/22561408
  9. http://www.ncbi.nlm.nih.gov/pubmed/19722820
  10. http://www.ncbi.nlm.nih.gov/pubmed/20226124
  11. Ghanem, T; Early, S (2006). “Vagal nerve stimulator implantation: An otolaryngologist’s perspective”. Otolaryngology – Head and Neck Surgery 135 (1): 46–51. doi:10.1016/j.otohns.2006.02.037. PMID 16815181.
  12. Tzu-Wei Lin  and Yu-Min Kuo (2013), “Exercise Benefits Brain Function: The Monoamine Connection” Brain Sci. 2013, 3, 39-53; doi:10.3390/brainsci3010039 (review paper in www.mdpi.com/2076-3425/3/1/39/pdf )
  13. Thierry Paillarda Yves Rollandb,c Philipe de Souto Barretob (2015) Protective Effects of Physical Exercise in Alzheimer’s Disease and Parkinson’s Disease: A Narrative Review. J Clin Neurol 2015;11(3):212-219 / http://dx.doi.org/10.3988/jcn.2015.11.3.212  –ttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507374/pdf/jcn-11-212.pdf
  14. Peter B. Schwarz, and  John H. Peever (2011), “Dopamine triggers skeletal muscle tone by activating D1-like receptors on somatic motoneurons” 
  15. http://www.ncbi.nlm.nih.gov/pubmed/8026408
  16. Lenzer J, Brownlee S. Why the FDA can’t protect the public. BMJ. 2010;341:c4753
  17. http://www.ncbi.nlm.nih.gov/pubmed/26728182
  18. http://www.sciencedaily.com/releases/2010/11/101102191841.htm
  19. http://www.ncbi.nlm.nih.gov/pubmed/24870622
  20. Doctor’s Guide: Vagus Nerve Stimulation Successful For Depression
  21. Neurology Channel: Vagus Nerve Stimulation
  22. FDA Summary of VNS Data
  23. Donovan, Charles E. (2006). Out of the Black Hole: A Patient’s Guide to Vagus Nerve Stimulation and Depression. Wellness Publishers. ISBN 978-0-9748484-3-3
  24. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245370/
  25. http://center4research.org/nrc-in-the-news/news-analysis-interviews-op-eds-editorials/medical-devices-that-can-kill/
  26. http://www.ncbi.nlm.nih.gov/pubmed/20950355
  27. Groves, Duncan A.; Brown, Verity J. (2005). “Vagal nerve stimulation: A review of its applications and potential mechanisms that mediate its clinical effects”. Neuroscience & Biobehavioral Reviews 29 (3): 493. doi:10.1016/j.neubiorev.2005.01.004.
  28. http://www.ncbi.nlm.nih.gov/pubmed/25556801
  29. Clinical trial number NCT00294281 for “Vagus Nerve Stimulation for Treating Adults With Severe Fibromyalgia” atClinicalTrials.gov
  30. Karason K, Mølgaard H, Wikstrand J, Sjöström L (April 1999). “Heart rate variability in obesity and the effect of weight loss”. The American Journal of Cardiology 83 (8):1242–7. doi:10.1016/S0002-9149(99)00066-1. PMID 10215292.
  31. http://www.utdallas.edu/news/2010/8/9-4791_NIH-Grant-Supports-Profs-Search-for-Tinnitus-Cure_article.html[full citation needed]
  32. Herremans SC, Baeken C (September 2012). “The current perspective of neuromodulation techniques in the treatment of alcohol addiction: a systematic review” (PDF). Psychiatria Danubina 24 (Suppl 1): S14–20. PMID 22945180.
  33. Shen MJ, Shinohara T, Park HW, et al. (May 2011). “Continuous low-level vagus nerve stimulation reduces stellate ganglion nerve activity and paroxysmal atrial tachyarrhythmias in ambulatory canines”. Circulation 123 (20): 2204–12.doi:10.1161/CIRCULATIONAHA.111.018028. PMC 3101282. PMID 21555706.
  34. Sha Y, Scherlag BJ, Yu L, et al. (October 2011). “Low-level right vagal stimulation: anticholinergic and antiadrenergic effects”.Journal of Cardiovascular Electrophysiology 22 (10): 1147–53. doi:10.1111/j.1540-8167.2011.02070.x. PMID 21489033.
  35. http://www.ncbi.nlm.nih.gov/pubmed/24727611
  36. Levy ML, Levy KM, Hoff D, et al. (June 2010). “Vagus nerve stimulation therapy in patients with autism spectrum disorder and intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry”. Journal of Neurosurgery. Pediatrics 5(6): 595–602. doi:10.3171/2010.3.PEDS09153. PMID 20515333.
  37. http://www.ncbi.nlm.nih.gov/pubmed/24875100
  38. http://www.ncbi.nlm.nih.gov/pubmed/24719355
  39. Faris PL, Eckert ED, Kim SW, et al. (May 2006). “Evidence for a vagal pathophysiology for bulimia nervosa and the accompanying depressive symptoms”. Journal of Affective Disorders 92 (1): 79–90. doi:10.1016/j.jad.2005.12.047. PMID 16516303.
  40. Niederbichler AD, Papst S, Claassen L, et al. (September 2009). “Burn-induced organ dysfunction: vagus nerve stimulation attenuates organ and serum cytokine levels”. Burns 35 (6): 783–9. doi:10.1016/j.burns.2008.08.023. PMID 19482432.
  41. Abraham WT, Smith SA (February 2013). “Devices in the management of advanced, chronic heart failure”. Nature Reviews. Cardiology 10 (2): 98–110. doi:10.1038/nrcardio.2012.178. PMC 3753073. PMID 23229137.
  42. Payne BR, Tiel RL, Payne MS, Fisch B (May 2005). “Vagus nerve stimulation for chronic intractable hiccups. Case report”. Journal of Neurosurgery 102 (5): 935–7. doi:10.3171/jns.2005.102.5.0935. PMID 15926725.
  43. Effects of Vagus Nerve Stimulation (VNS) as a “Treatment of Persistent Depression With Comorbid Personality Disorders”.,cpapplanet.com
  44. Zamotrinsky, A. V.; Kondratiev, B.; de Jong, J. W. (2001). “Vagal neurostimulation in patients with coronary artery disease”. Auton. Neurosci. 88 (1-2): 109–116. doi:10.1016/S1566-0702(01)00227-2.
  45. Spatola M, Jeannet PY, Pollo C, Wider C, Labrum R, Rossetti AO (2013). “Effect of vagus nerve stimulation in an adult patient with Dravet syndrome: contribution to sudden unexpected death in epilepsy risk reduction?”. European Neurology 69 (2): 119–21.doi:10.1159/000345132. PMID 23207687.
  46. Zamponi N, Passamonti C, Cesaroni E, Trignani R, Rychlicki F (July 2011). “Effectiveness of vagal nerve stimulation (VNS) in patients with drop-attacks and different epileptic syndromes”. Seizure 20 (6): 468–74. doi:10.1016/j.seizure.2011.02.011.PMID 21396833.
  47. Yamakawa K, Matsumoto N, Imamura Y, et al. (2013). “Electrical vagus nerve stimulation attenuates systemic inflammation and improves survival in a rat heatstroke model”. Plos One 8 (2): e56728. doi:10.1371/journal.pone.0056728. PMC 3570456.PMID 23424673.
  48. Liu H, Liu Y, Yu J, et al. (April 2011). “Vagus nerve stimulation inhibits heroin-seeking behavior induced by heroin priming or heroin-associated cues in rats”. Neuroscience Letters 494 (1): 70–4. doi:10.1016/j.neulet.2011.02.059. PMID 21362452.
  49. Krzyzaniak M, Peterson C, Loomis W, et al. (May 2011). “Postinjury vagal nerve stimulation protects against intestinal epithelial barrier breakdown”. The Journal of Trauma 70 (5): 1168–75; discussion 1175–6. doi:10.1097/TA.0b013e318216f754.PMID 21610431.
  50. http://livingwithlgs.com/vagus-nerve-stimulation.aspx
  51. Ghacibeh GA, Shenker JI, Shenal B, Uthman BM, Heilman KM (September 2006). “The influence of vagus nerve stimulation on memory”. Cognitive and Behavioral Neurology 19 (3): 119–22. doi:10.1097/01.wnn.0000213908.34278.7d. PMID 16957488.
  52. Rosenberg O, Shoenfeld N, Kotler M, Dannon PN (June 2009). “Mood disorders in elderly population: neurostimulative treatment possibilities”. Recent Patents on CNS Drug Discovery 4 (2): 149–59. doi:10.2174/157488909788453013. PMID 19519563.
  53. Jump up^ Polak T, Zeller D, Fallgatter AJ, Metzger FG (March 2013). “Vagus somatosensory-evoked potentials are prolonged in patients with multiple sclerosis with brainstem involvement”. Neuroreport 24 (5): 251–3. doi:10.1097/WNR.0b013e32835f00a3.PMID 23407276.
  54. Li H, Yang TD (November 2009). “Vagus nerve stimulation may be used in the therapy of myocarditis”. Medical Hypotheses 73 (5): 725–7. doi:10.1016/j.mehy.2009.04.036. PMID 19481875.
  55. http://www.ocdcentral.info/tag/vagus-nerve-stimulation
  56. Payrits T, Ernst A, Ladits E, Pokorny H, Viragos I, Längle F (October 2011). “Vagale Stimulation–eine neue Möglichkeit zur konservativen Therapie der peripheren arteriellen Verschlusskrankheit” [Vagal stimulation – a new possibility for conservative treatment of peripheral arterial occlusion disease]. Zentralblatt Für Chirurgie (in German) 136 (5): 431–5. doi:10.1055/s-0031-1283739. PMID 22009541.
  57. Xiong J, Xue FS, Liu JH, et al. (December 2009). “Transcutaneous vagus nerve stimulation may attenuate postoperative cognitive dysfunction in elderly patients”. Medical Hypotheses 73 (6): 938–41. doi:10.1016/j.mehy.2009.06.033. PMID 19631475.
  58.  Grujic J, Bien CG, Pollo C, Rossetti AO (January 2011). “Vagus nerve stimulator treatment in adult-onset Rasmussen’s encephalitis”. Epilepsy & Behavior 20 (1): 123–5. doi:10.1016/j.yebeh.2010.10.024. PMID 21130042.
  59. Jump up^ Steinberg H (July 2013). “A pioneer work on electric brain stimulation in psychotic patients. Rudolph Gottfried Arndt and his 1870s studies”. Brain Stimulation 6 (4): 477–81. doi:10.1016/j.brs.2012.11.004. PMID 23266132.
  60. Jump up^ Kumar V, Sharma A (January 2010). “Is neuroimmunomodulation a future therapeutic approach for sepsis?”. International Immunopharmacology 10 (1): 9–17. doi:10.1016/j.intimp.2009.10.003. PMID 19840870.
  61. Lyubashina OA, Sokolov AY, Panteleev SS (October 2012). “Vagal afferent modulation of spinal trigeminal neuronal responses to dural electrical stimulation in rats”. Neuroscience 222: 29–37. doi:10.1016/j.neuroscience.2012.07.011. PMID 22800563.
  62. Hiraki T, Baker W, Greenberg JH (April 2012). “Effect of vagus nerve stimulation during transient focal cerebral ischemia on chronic outcome in rats”. Journal of Neuroscience Research 90 (4): 887–94. doi:10.1002/jnr.22812. PMC 3306061.PMID 22420043.
  63. Levy G, Fishman JE, Xu D, et al. (January 2013). “Parasympathetic stimulation via the vagus nerve prevents systemic organ dysfunction by abrogating gut injury and lymph toxicity in trauma and hemorrhagic shock”. Shock 39 (1): 39–44.doi:10.1097/SHK.0b013e31827b450. PMC 3547655. PMID 23247120.
  64. Lopez NE, Krzyzaniak MJ, Costantini TW, et al. (June 2012). “Vagal nerve stimulation decreases blood-brain barrier disruption after traumatic brain injury”. The Journal of Trauma and Acute Care Surgery 72 (6): 1562–6. doi:10.1097/TA.0b013e3182569875.PMID 22695423.
  65. Kumaria A, Tolias CM (June 2012). “Is there a role for vagus nerve stimulation therapy as a treatment of traumatic brain injury?”.British Journal of Neurosurgery 26 (3): 316–20. doi:10.3109/02688697.2012.663517. PMID 22404761.
  66. Komisaruk BR, Whipple B, Crawford A, Liu WC, Kalnin A, Mosier K (October 2004). “Brain activation during vaginocervical self-stimulation and orgasm in women with complete spinal cord injury: fMRI evidence of mediation by the vagus nerves”. Brain Research1024 (1-2): 77–88. doi:10.1016/j.brainres.2004.07.029. PMID 15451368.
  67.  Whipple B, Komisaruk BR (2002). “Brain (PET) responses to vaginal-cervical self-stimulation in women with complete spinal cord injury: preliminary findings”. Journal of Sex & Marital Therapy 28 (1): 79–86. doi:10.1080/009262302317251043.PMID 11928182.
  68. http://clinicaltrialsfeeds.org/clinical-trials/show/NCT01260090
  69. Zhang X, Cao B, Yan N, et al. (January 2013). “Vagus nerve stimulation modulates visceral pain-related affective memory”.Behavioural Brain Research 236 (1): 8–15. doi:10.1016/j.bbr.2012.08.027. PMID 22940455.
  70. George, M; Sackeim, HA; Rush, AJ; Marangell, LB; Nahas, Z; Husain, MM; Lisanby, S; Burt, T; et al. (2000). “Vagus nerve stimulation: A new tool for brain research and therapy*”. Biological Psychiatry 47 (4): 287–95. doi:10.1016/S0006-3223(99)00308-X. PMID 10686263.
  71.  “UCLA Develops Unique Nerve-stimulation Epilepsy Treatment; “Brain Pacemaker” Designed as External or Implant Device”(Press release). 2006-07-25. Retrieved 2006-07-26.
  72. Lenzer J. Watching over the medical device industry. The BMJ. 2009;338:b2321.
  73.  bit.ly/1jWXnNc
  74. http://www.vnsmessageboard.com/index.php/topic,4476.0.htm
  75. http://www.vnsmessageboard.com/index.php/topic,3842.0.htm
  76.  http://www.vnsmessageboard.com/index.php/topic,3850.0.htm
  77.  http://www.vnsmessageboard.com/index.php/topic,4008.0.htm
  78. http://www.vnsmessageboard.com/index.php/topic,4011.0.htm
  79. http://www.vnsmessageboard.com/index.php/topic,3832.0.htm
  80. http://www.vnsmessageboard.com/index.php/topic,3862.0.htm
  81. http://www.vnsmessageboard.com/index.php/topic,3868.0.htm
  82. Malow, BA; Edwards, J; Marzec, M; Sagher, O; Fromes, G (2000). “Effects of vagus nerve stimulation on respiration during sleep: A pilot study”. Neurology 55 (10): 1450–4. doi:10.1212/wnl.55.10.1450. PMID 11094096.
  83. Marzec, Mary; Edwards, Jonathan; Sagher, Oren; Fromes, Gail; Malow, Beth A. (2003). “Effects of Vagus Nerve Stimulation on Sleep-related Breathing in Epilepsy Patients”. Epilepsia 44 (7): 930–5. doi:10.1046/j.1528-1157.2003.56202.x. PMID 12823576.
  84. “HP-5A: Heart Rate and Blood Pressure” (PDF). iWorx Systems Inc. Retrieved 12 May 2014.
  85. Hsieh, T; Chen, M; McAfee, A; Kifle, Y (2008). “Sleep-Related Breathing Disorder in Children with Vagal Nerve Stimulators”.Pediatric Neurology 38 (2): 99–103. doi:10.1016/j.pediatrneurol.2007.09.014. PMID 18206790.
  86. Marzec, Mary; Edwards, Jonathan; Sagher, Oren; Fromes, Gail; Malow, Beth A. (2003). “Effects of Vagus Nerve Stimulation on Sleep-related Breathing in Epilepsy Patients”. Epilepsia 44 (7): 930–5. doi:10.1046/j.1528-1157.2003.56202.x.PMID 12823576.
  87. Vaughn, B; Dcruz, O; Beach, R; Messenheimer, J (1996). “Improvement of epileptic seizure control with treatment of obstructive sleep apneoa”. Seizure 5 (1): 73–8. doi:10.1016/S1059-1311(96)80066-5. PMID 8777557.
  88. Bernards, Christopher M. (2004). “An Unusual Cause of Airway Obstruction during General Anesthesia with a Laryngeal Mask Airway”. Anesthesiology 100 (4): 1017–8. doi:10.1097/00000542-200404000-00037. PMID 15087642.
  89. “Vagus Nerve Stimulation”. University of Michigan Depression Center. Retrieved 28 August 2013.
  90. Hatton, Kevin W.; McLarney, J Thomas; Pittman, Thomas; Fahy, Brenda G. (2006). “Vagal Nerve Stimulation: Overview and Implications for Anesthesiologists”. Anesthesia & Analgesia 103 (5): 1241–9. doi:10.1213/01.ane.0000244532.71743.c6.
  91. http://www.fda.gov/ohrms/dockets/AC/97/transcpt/3299t1.pdf
  92. http://www.vnsmessageboard.com/index.php/topic,4117.0.htm
  93. Tracey, Kevin J. (2007). “Physiology and immunology of the cholinergic antiinflammatory pathway”. Journal of Clinical Investigation 117 (2): 289–96. doi:10.1172/JCI30555. PMC 1783813. PMID 17273548.
  94. Rosas-Ballina, M.; Ochani, M.; Parrish, W. R.; Ochani, K.; Harris, Y. T.; Huston, J. M.; Chavan, S.; Tracey, K. J. (2008). “Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia”. Proceedings of the National Academy of Sciences 105 (31): 11008–13Jump up^ Tracey, Kevin J. (2009). “Reflex control of immunity”. Nature Reviews Immunology 9 (6): 418–28. doi:10.1038/nri2566.PMID 19461672.
  95. ^ Rosas-Ballina, M.; Olofsson, P. S.; Ochani, M.; Valdés-Ferrer, S. I.; Levine, Y. A.; Reardon, C.; Tusche, M. W.; Pavlov, V. A.; Andersson, U.; Chavan, S.; Mak, T. W.; Tracey, K. J. (2011). “Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit”. Science 334 (6052): 98–101. doi:10.1126/science.1209985.
  96.  Cyberonics, Inc. (2007.) VNS Therapy Patient Essentials: Depression.
  97.  Panescu, D. (2005). “Emerging Technologies: Vagus Nerve Stimulation for the Treatment of Depression”. IEEE Engineering in Medicine and Biology Magazine 24 (6): 68–72. doi:10.1109/MEMB.2005.1549737.
  98.  Leusden, J; Sellare, R; et al. (2015). “Transcutaneous Vagal Nerve Stimulation (tVNS): a new neuromodulation tool in healthy humans?”. Frontiers in Psychology 6 (102): 287–95. doi:10.3389/fpsyg.2015.00102. PMC 4322601.

Excessive Orgasm, Over-Masturbation or Over-ejculation Induced Sexual Exhaustion Symptoms for men and women

Excessive Orgasm, Over-Masturbation or Over-ejculation Induced Sexual Exhaustion Symptoms for men and women


Special Note: The main difference between masturbation (self-pleasure) and lovemaking is the oxytocin release. Lovemaking usually stimulates the pituitary gland to release oxytocin while masturbation won’t.  Oxytocin can help the post-orgasm or post-ejaculation recovery by retaining the arterial dilation and relaxation in the brain and genital area.  Psychologically,  oxytocin lets the lovemaking couples feel being loved.

Chronic over-masturbation, over-ejaculation or excessive orgasm generally burn out your dopamine, cholinergic/vagal(acetylcholine) , serotonin and GABA nervous control with excessive hypothalamic and adrenal dopamine-norepinephrine conversion for constant sympathetic nervous fight or/and flight, excessive norepinephrine-induced informatory hormone prostaglandin E2 production over your body cells from your head to your toe, excessive norepinephrine-induced Immunoglobulin (antibodies such as IgA, IgD, IgE, IgG and IgM) elevation for neuroimmune weakness and disorders, constant elevation of the pituitary prolactin release for autoimmune disorders, and constant constriction and inflammation of your arterial and heart smooth muscles.
Chronic elevation of sex-induced excessive norepinephrine and prostaglandin E2 in the limbic system and central nervous system with a weak serotonin and GABA nervous control result in brain evolution, known as neuroplasticity, for addiction of sexual pleasure rewarding; with the neuroplasticity, excessive sympathetic nervous and prostaglandin E2 stimulation on the sex organs, such as the penis, prostate,  and seminal vesicles for men and the clitoris, vagina, cervix and uterus for women,  facilitate constant in-heat inflammation and erection for persistent sexual arousal for frequent, sexual orgasmic addiction. To reverse the brain evolution of sexual addiction, you will have to power up your cholinergic, serotonin and GABA nervous control on your hypothalamic and adrenal dopamine-norepinephrine conversion.  Brain evolution is a long-term process. It can be in either the positive or negative direction, depending what stimulation the brain and central nervous system get. Generally, cholinergic/vagal nervous stimulation in conjunction with restoration of serotonin and GABA nervous control will produce positive brain evolution for good.
Over-masturbation/over-ejaculation/excessive-orgasm can castrate the hypothalamus-pituitary-testicular(ovarian) axis by arterial constriction and inflammatory narrowness in your brain and pelvic organs (testicles, prostate, seminal vesicles, penis, ovaries, uterus, vagina and clitoris) due to excessive release of prolactin, norepinephrine, and epinephrine, excessive binding of norepinephrine/epinephrine on the alpha-adrenergic receptors, the norepinephrine/epinephrine induced excessive prostaglandin E2, and the post-sex deficiency of nitric oxide and prostaglandins E1/E3 production. As a result of arterial constriction and inflammatory narrowness (leading to 
arterial thrombosis and atherothrombosis!

http://jem.rupress.org/cgi/content/full/204/2/311  ),
your brain, testicles, penis, (clitoris, vulva, G-spot, vagina, uterus and ovaries for women)  feet and hands get low blood supplies and less androgen hormones and nuerochemicals, but more inflammatory hormone production and stress hormones.  And, it will take a long time for you to get recovery from sexual exhaustion and post-sex inflammation. You may also wonder why your  penis or clitoris go limps and your vagina become dry in the middle of sex.  When your adrenal and testicular (or ovarian) function are disabled, you will have to rely on the skin neruoendocrine function to elevate your androgen hormones.  Please also note that prostaglandin E2 also inflame veins too –
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=199422, and
http://atvb.ahajournals.org/cgi/content/full/17/9/1644 . When you get inflamed arteries and veins, your blood circulation won’t reach the inflamed areas and you will experience pain, numbness or cramp .  As for sex, you don’t want inflamed arteries and veins in your penis and testicles (clitoris, labia, G-spot,  vagina. uterus (and its support ligaments and tissues) and ovaries for women), do you?

In addition, excessively accumulation of prolactin as a result of  high-frequency ejaculation or orgasm disables the activin release from the testicles, epididymis, prostate,and seminal vesicles (or ovaries for women),  leading to a low pituitary FSH release, followed by a low pituitary LH release, resulting in deficiency of androgen hormonal production from the testicles and ovaries. On the other hand, activin is a negative regulator of prolactin and cell growth ( http://mend.endojournals.org/cgi/content/full/18/6/1558 ). Without sufficient activin, the excessive release prolactin becomes persistent,  and thus the androgen hormones (testosterone and DHT) level remains too low to help the exhausted hypothalamus-pituitary-adrenal and testicular (ovarian) axis to recover from sexual exhaustion or post-sex illness or to suppress the inflammatory pains. No wonder, you will experience persistent  sexual exhaustion, fatigue, tiredness and inflammatory pains. 

Excessive orgasm, over-masturbation or over-ejaculation over-discharges the brain’s acetylcholine, dopamine, and serotonin nerves systems, resulting in brain’s/nervous (pro-sympathetic, due to over-conversion of dopamine to norepinephrine and epinephrine for stress responses), liver, cardiovascular, kidney, and endocrine disorder, and then burns them out with chronically excessive norepinephrine/epinephrine/sympathetic nervous fires, the induced inflammatory hormone prostaglandin E2, glutamate, histamine,  3,4-dihydroxyphenylacetaldehyde (DOPAL – http://parkinsons.hopedigest.com/blogs/scientists_indict_dopal_as_cause_of_parkinsons_disease
); dihydroxyphenylacetic acid (DOPAC –
http://www.ohiolink.edu/etd/send-pdf.cgi?acc_num=kent1164141349 and
),3,4-dihydroxyphenylglycolaldehyde (DOPEGAL –
) and 3,4-dihydroxyphenylglycol (DHPG –
http://pharmrev.aspetjournals.org/cgi/reprint/56/3/331 ).
Your brain/neuro-endocrine and liver systems are like an over-discharged good-old-day car battery (overcharge causes chemical/mineral deposits on the electrodes of acid batteries made before 1980 and ruin them)  which won’t start the engine to perform recharging for itself.  Some nervous cells are burned out or damaged by the nervous excitotoxicity and inflammation byproducts listed above.   As a result of the exhaustion of your pituitary-adrenal and -testicular axis,  the production of your androgen hormones (DHEA, androstenedione testosterone and DHT) and pituitary oxytocin become too low to support your neuro-immune function and to suppress the inflammatory hormone prostaglandin E2 release from your body – typically from your brain/head/neck, your pelvic organs, and your internal organs between your neck and pelvic cavity.  The excess- orgasm or over-ejaculation induced prolactin,  cortisol, norepinephrine and epinephrine,  if excessive,  can disable the pituitary-testicular (or -ovarian) axis for a few days or even months, leading to a long refraction time or a long-term sexual exhaustion and inflammation.  Even, excessive prolactin,  cortisol, noepinephrine and/or epinephrine in the bloodstream can induce excessive prostaglandin E2 release from the tissues. In fact, chronic elevation of epinephrine and prostaglandin E2 result in nervous excitotoxicity and cellular damage in the brain cells and the vagal or parasympathetic nerves in the liver, lungs, adrenal, heart, blood vessels, digestive system, pancreas, gallbladder, ovaries, uterus, cervix, testicles and prostate.  Men also suffer from deficiency of the key semen chemicals such as potassium, zinc, calcium, magnesium, citric acid, androgen hormones (DHEA, androstenedione, testosterone and DHT), fructose, phosphorylcholine (for the brain/memory/vision/hearing/nervous sensing systems), spermine, prostatic acid phosphatase, free amino acids (most important ones includes GABA, glycine,  agmatine and 5-HTP associated with brain/liver/adrenal/testicular functions, vision, hearing,  sympathetic nervous control and mood) , prostaglandins (prostaglandins E1 and E3 for the elasticity and flexibility of tissues, nerves and blood vessels) and enzymes that support the androgen hormones and neurotransmitter syntheses. Unfortunately, the sexual exhaustion symptoms and inflammatory responses are a result of a low DHEA, androstenedione testosterone,  DHT and/or oxytocin with a high or excessive level of prolactin, cortisol, norepinephrine and epinephrine, although you won’t see a drop of your androgen hormones in couple hours right after the orgasm-induced prolactin and cortisol release.  However, you may experience the  pro-inflammatory neuro-immune responses to the sex-induced stress hormones norepinephrine and epinephrine  during sex arousal and orgasm/ejaculation  or even several days by activating  a group of proinflammatory cytokines such as IL-1, IL-1ß, IL-6, TNF-, IFN-, and MIP-1 and protein kinases A and C  in the the immune system via the alpha- and beta-adrenergic receptors in cells.  The proinflammatory cytokines, acting as the endogenous pyrogen of desire fires, can trigger excessive norepinephrine-induced prostaglandin E2 production in the adrenergic receptors everywhere, from your scalp down to your toes. And then epinephrine will induces cutaneous mechanical hyperalgesia and sensitizes the dorsal root ganglion neurons via its action at a -adrenergic receptor and the effects of epinephrine are enhanced by both the inflammatory protein kinases A and  C second-messenger pathways for enhancement of inflammatory responses.  When the elevated prolactin, cortisol, norepinephrine and epinephrine constrict your arteries to your liver,  kidneys, adrenal glands and testicles (ovaries for women) after sex, your adrenal and testicular (or ovarian) function will be disabled or shut down for many hours or days –http://www.actionlove.com/#Ejaculation%20Frequency%20vs.%20Testosterone%20Level
Suppression of androgen hormones production by excessive prolactin and cortisol, in conjunction with constriction of the arteries in the brain, liver, adrenal glands and testicles, will continue weakening your neuro-immune reaction for proinflammation, and prolong your recovery time and post-orgasm/post-ejaculation exhaustion and illness –http://www.actionlove.com/#Sexually%20Stress-induced%20Inflammatory%20Pains,
Warning: sexual arousal, ejaculation or orgasm won’t decrease your androgen hormonal level in the bloodstream immediately. If sexual arousal fires up your cortisol and prolactin to let your penis go limp (the sympathetic nervous Flight response to sexual stimulation and stress), you give up sexual activities immediately. This is because the elevation of prolactin and cortisol block your hypothalamus-pituitary-adrenal and -testicular axis which are supposed to fire up oxytocin, DHEA, androstenedione, testosterone and DHT production for your ongoing sexual excitation and orgasm. I consider that going limp  during sex is a natural protection of your hypothalamus-pituitary-adrenal and -testicular axis.  If you force yourself to ejaculation or orgasm after your experience the erectile dysfunction during sex, you will be in trouble. This is because, once androgen hormones in the bloodstream are used up and become too low to support your brain/nerves, internal organs and joints/muscles, you will start to experience the post-orgasm/post-ejaculation sexual exhaustion symptoms.  Generally, these symptoms start to show up at about 3-8 hours after ejaculation or orgasm. The symptoms can last for 3-10 days until your brain’s hypothalamus-pituitary-adrenal and-testicular axis start to kick in. During this suffering period, you have to rely on your skin/tissue’s Cutaneous Hypothalamus-Pituitary-Adrenal (CHPA) function to assist post-ejaculation or post-orgasm recovery. Due to the link of the hypothalamus-pituitary-thyroid axis, you may also experience the symptoms associated with thyroid disorders. You will also like to experience hair loss too ( http://www.actionlove.com/extra/hailoss.htm  ) For the functional equivalent of human hair follicles to the hypothalamus-pituitary-adrenal (HPA) axis, please readhttp://www.fasebj.org/cgi/reprint/04-1968fjev1 (also http://edrv.endojournals.org/cgi/reprint/21/5/457). When excessive sex stressed out your HPA, it also burned out your hair follicles, in particularly, with a high DHT, inflammatory hormone prostaglandin E2, cortisol, norepinephrine and epinephrine level and with a constriction of the blood vessels in your scalp when chronic prolactin, norepinephrine and epinephrine level run high.  You can get more information form the home page of  http://actionlove.com for more detail. Using prescribed erectile drugs, the PDE-5 inhibitors,  to assist erection for sex will mess up your neuro-endocrine function for sexual exhaustion. 
Please also note that the extremely exhausted adrenal function can cause an extreme low level of  DHEA, endophrin and cortisol. An abnormal cortisol level or a lack of endorphin indicates the adrenal function disorder, fatigue or excessive orgasm/ejaculation induced stress. Excessive orgasm or over-ejaculation can produce a transient shooting or cortisol and epinephrine and result in a long-term effect on the adrenal function, although the cortisol output may become too low or too high few days after sexual activities, with a constant elevation of epinephrine released from the hypothalamus and the adrenal medulla.  It should be aware that prostaglandin E2 is an immune suppressor, as well as an nervous excitor.  Excessive prostaglandin E2 in the bloodstream causes not only inflammatory, but also weak neuro-immunity.   As a result, sexual exhaustion produce multiple symptoms which become UFO for the western doctors and medical societies since the western doctors and medical societies fail to realize the root of the problems, “enjoying too much sexual pleasure.” If you don’t go after the root of the problems, there is no way to solve the sexual exhaustion symptoms. For more information or our over-10-year collection of sexual exhaustion symptoms, please go to
http://www.actionlove.com/extra/over2.htm  and

Orgasm induces immune challenge in 2 ways: direct and indirect. The direct one is to respond to the foreign substances bringing to the contact organs including the mouth and sex organs. The indirect one is a neuro-immune response to the orgasm induced norepinephrine release from the hypothalamus and adrenal glands, leading to the elevation of Immunoglobulin (antibodies ). The problem is: Chronic elevation of the stress hormone norepinephrine and its induced immune suppression will collapse the immune system. There are several symptoms associated with excessive norepinephrine-induced Immunoglobulin (antibodies such as IgA, IgD, IgE, IgG and IgM) elevation and excessive immune-suppression prostaglandin E2 for neuroimmune weakness and disorders. For sexual induced asthma, sneezing, allergy and sinus, we will have to deal with the excessive norepinephrine induced IgE which triggers excessive release of both histamine and prostaglandin E2.
The antibody IgE, which is found in the lungs, skin, and mucous membranes, is responsible for activation of mast cells to release histamine,  and  for triggering cytokines like interleukin-4 (IL-4) and interleukin-13 (IL-13) and other inflammatory mediators to release inflammatory hormone and immune-suppressor prostaglandin E2.  Thus, overshooting of IgE causes allergy, sneezing and hypersensitivity.  Elevation of the stress neurohomrone norepinephrine will generally trigger the elevation of IgE for allergy, sneezing and hypersensitivity,  and activates enzyme Cyclooxygenase-2 (also known as COX-2) to oxidize arachidonic acid into prostaglandin E2.  Excessive psychological or physical stress, excessive sex, over-exposure to sunlight or intensive heat, air pollution, or pollen can overshoot IgE for allergy, sinus, headaches and other inflammatory diseases.
IgM is found in blood and lymp fluid in response to an infection. It promotes other immune system cells to destroy intruders. However,  Excessive elevation of IgM indicates ectodermal dysplasia and immunodeficiency, or humoral immune defect.
IgG is found in the body fluid, very important in fighting against bacterial and viral infections. Norepinephrine is not supposed to increase IgG antibodies.
IgA is found in the areas of the body, that exposed to foreign substances. Those areas include the nose, breathing passages, digestive tract, ears, eyes, and vagina. IgA antibodies protect the body surfaces  against outside foreign substances. Sexual intimacy may elevate IgA  in response to the secretion from the mouth, vagina, uterus and  cervix and other sexual aid substances for men, and to the secretion of mouth, the ejaculation fluid and sexual aid substances for women. It is supposed to be an immune challenge.
Chronic over-stimulation of the immune system with excessive stress neurohormone norepinephrine and its induced immune suppressor prostaglandin E2 will breakdown the immune adaptive ability  and collapse the the adaptive immune system, leading to immune disorders. Thus, if your norepinephrine and prostaglandin E2 are not overshooting, immune stimulation with norepinephrine will improve the adaptive immune system to combat pathogens, the alternative term “infectious agents” or the common name “germs.”
The other immune complements of the innate immune system,  known as the complement system which is not adaptable and won’t change overtime in an individual’s lifetime, can be recruited and brought into action by the adaptive immune system. The complement system is a biochemical cascade that clears pathogens by attacking the surface of foreign cells. It contains over 20 different proteins, circulating in the blood and bathing the tissues in an inactive form.  In response to the recognition of  foreign cells, the proteins become sequentially activated, working in a cascade  in which the binding of one protein will promote the binding of the next protein in the cascade. It is the major humoral component of the innate immune response.
The complement cascade is a double-edged sword.  While protecting against the invasion of foreign cells, the complement system has the potential to be extremely damaging to host tissues via its induced inflammation and phagocytosis. A long-term stimulation of the complement system may lead to many diseases associated with an immune component, such as Barraquer-Simons Syndrome, asthma, lupus erythematosus, glomerulonephritis, vasculitis (inflammatory destruction of blood vessels including both arteries and veins)), kidney basement membrane diseases, nephritis (kidney inflammation), hemolysis (rupture of red blood cells), arthritis, autoimmune heart disease, multiple sclerosis, inflammatory bowel disease,  ischemia-reperfusion injuries, and autoimmune disorders,   and to the diseases of the central nervous system such as Alzheimer’s disease, Parkinson’s diseases,  parkinsonism,  and other neurodegenerative conditions.

The sexual exhaustion symptoms include:
1. daily or orgasmic/ejaculation pains or cramps in pelvic cavity – including low back, tail bone, perineum, groins, perineum, penis (clitoris/vagina for women during penetration, intercourse, orgasm or post orgasm), testicles, low abdomen, neck/shoulders or rear brain (or whole head)– due to a lack of the relaxation and tissue-elastic hormone prostaglandin E-1 synthesized by the local tissues, an abrupt drop of the brain’s neurotransmitters acetylcholine, dopamine, serotonin and GABA, or an excessive conversion of the dopamine->norepinephrine->epinephrine.
2. depression, stress , anxiety, and emotional instability (Mood Swing)  – due to deficiency of the neurotransmitters acetylcholine, dopamine, serotonin add GABA.
3. Attention Deficiency and Absence mind (losing mind concentration and memory) – due to the deficiency of the brain’s neurotransmitters serotonin and acetylcholine – memory protection failure or insufficient memory.
4. eye floaters or sun-light sensitive eyes, blurred vision  or sympathetic nervous pupil dilation  – due to disorders of the nervous sensing (acetylcholine nervous)  and amplifier (dopamine nervous) circuits,  a deficiency of the serotonin/GABA nervous modulation in retina, excessive stress hormones, or a poor retinal blood circulation or an arterial constriction due to deficiency of prostaglandin E-1 or/and Nitric oxide or sympathetic nervous action on the beta receptors, or an excessive inflammatory hormone prostaglandin E2 release induced by deficiency of the androgen hormones or excessive stressors cortisol or epinephrine.
5. buzzing ears – the same as Item 4..
6. less or no seminal/lubrication production (vaginal dryness for women and VAGINISMUS ),  weak ejaculation or ejaculation dysfunction – watery ejaculation or no ejaculation or orgasm – due to the neuro-endocrine disorder resulting from the weakening liver, adrenal, prostate and testicular (ovarian) functions.  This is the destruction of seminal production mechanism for men. For women, it is due to a low estrogen and androstenedione/testosterone/prostaglandin E-1/oxytocin or/and a high progesterone level in the bloodstream.
7. weak erection or youth impotence.
8. low libido, exhaustion and fatigue  due to deficiency of the brain’s neurotransmitters dopamine, acetylcholine and serotonin and a lack of oxytocin.
9. prostatitis or urethitis ( the abrasion of the prostate or urethral duct; easier to have prostate/urethral/bladder infection) urinary or bowel incontinencepelvic pains (Interstitial Cystitis (IC) testicular painspenile pains, andclitoral numbness or pains as a result of excessive inflammatory prostaglandin E-2 release with a deficiency of healing hormone prostaglandin E-1 – disorders of the 3rd brain – the pelvic parasympathetic nerves S1-S5 and Co and the serotonin nervous modulators for the sympathetic T10-L2,  particularly the L1 and L2 nervous branches to the bladder, urethra, prostate, bulbourethral glands, Great Vestibular glands, Urethral glands (de-generated seminal vesicles), clitoris, vagina, uterus and rectum/anus.  men produces excessive pre-cum and women are vaginally over-wetted.  Men or women may experience sex-/orgasm-induced stress incontinence (leakage or ejaculation of urine during sex or orgasm).
10. penile (clitoral or G-spot for women) shrinkage ( or vaginal enlargement or loosening for women) – due to atrophy of spongy tissues caused by nervous damage, deficiency of acetylcholine or/and Nitric Oxide,  or excessive stress hormone in the sympathetic alpha receptors.
11. unwanted penile bending and shrinking (the clitoral/G-spot death and shrinkage)- formation of the scar tissues due to tissue and nervous abrasion .
12. premature ejaculation – damage of the prostate/urethral nerves and duct, and burning-out (drop) of the serotonin and acetylcholine level in the brain and nervous synapses.
13. premature hair loss or decoloring.
14. short breathing and irregular cardiovascular output (sympathetic) – a weakening brain’s acetylcholine/serotonin and parasympathetic/vagus nervous function.
15. white or violet nails – deficiency of Zinc.
16. weak immunity – neuro-immune disorder resulting from the deficiency of the neurotransmitters acetylcholine (Yin Chi) and dopamine (Yang Chi).  For example, easy to catch cool or get sick and requiring a longer time to get recovery from sickness.
17. Sleeping disorder and its associated symptoms- due to the deficiency of serotonin and melatonin, both of which are synthesized by the pineal gland with GABA and norepinephrine, or due to excessive pituitary LH and FSH hormones in an attempt to revive a weak/dying testicular/ovarian function, or due to excessive Yang-type stressor epinephrine in the cerebrospinal fluid. This causes a deficiency hGH and excessive inflammatory hormone prostaglandin E-2 release into the bloodstream, an undercharging of the parasympathetic nervous system, and an excessive sympathetic nervous fire (Flight or Fight), resulting in back/joint/ligament pains or crampsurinary or bowel incontinence, Irritable Bowel Syndrome (IBS),  prostatitis or urethritis, as a result of no or insufficient healing (restoration)  power (prostaglandin E-1) in the organs. muscles, ligaments and joints. Please note that excessive Ying-type stressor cortisol causes hGH, DHEA and testosterone deficiency and  induces drowsiness over-sleeping, blurred vision, and hangover.
18. organ functional disorders in the 2nd brain (between the neck and pelvis) due to the weakening of the vagus (parasympathetic) nerves and the weakening serotonin nervous modulation on the sympathetic nervous functions – the most typical ones are: digestive , cardiovascular and liver systems; some experience the gallbladder and pancreas functional disorders too. The most visual or sensible disorder is stomach pain or digestive panic.
19. Excessive Sweating – the sympathetic/epinephrine nervous fires burning the entire body due to an constantly excessive dopamine/norepinephrine-epinephrine conversion in the hypothalamus and adrenal medulla.
20. Headaches or migraines – due to excessive inflammatory hormone prostaglandin E-2 release and excessive dopamine/norepinephrine-epinephrine conversion in the brain after the acetylcholine, serotonin and GABA nervous system were exhausted by excessive sex.
21. Fatigue, tiredness and exhaustion – the parasympathetic nervous recharging/healing system is out of order; the pituitary releases excessive prolactin to shut down the testicular function.
22. Muscle weakness – due to deficiency of DHEA, testosterone or DHT. This results from exhaustion of the hypothalamus-pituitary-adrenal and/or testicular axis.
23. Muscle Tremors/Twitching (pre-Parkinson’s symptoms) – due to deficiency of dopamine and acetylcholine.
24. Weak neuro-immune function and persistent inflammation – easy to get infection or catch flu or cold, sinus, allergy, or/and sore throat.
25. Kidney inflammatory pains – orgasm over-stimulates the immune complement system, resulting kidney inflammation.

A weak adrenal function can constantly convert dopamine into norepinephrine and epinephrine for sympathetic nervous fire even your hypothalamus won’t get stimulated or excited. The Traditional Chinese Medicine terms this phenomenon as “Weak Kidney” .

(References: Sato, A. “Neural mechanisms of somatic sensory regulation of catecholamine secretion from the adrenal gland.” Adv Biophys. 1987;23:39-80. http://www.ncbi.nlm.nih.gov/pubmed/3326403

The effects of THC and testosterone on erectile function during copulation

The effects of THC and testosterone on erectile function during copulation

This is a question from a 50-year-old marijuana user which experience erectile dysfunction and premature ejaculation while his testosterone level is 1300 ng/dl.  Based up our collection of similar cases in http://www.actionlove.com/extra/marijuana.htm, we can conclude the erectile function, despite of a very high testosterone level,  results from the blunted dopaminergic function  by THC. Premature ejaculation is a result of excessive prostaglandin E2 and histamine in the prostate fluid and the bulbourethal fluid (also known as precum). Both  prostaglandin E2 and histamine turn on the sympathetic orgasm/ejaculation nervous control reflex in Disc L1-L3 from its sensory input in  the urethra, prostate and seminal vesicles. THC vs testosterone on erectile functionReader’s Question:
I’m a 50 year old male who has been dx with transverse myelitis in my T-11 area. My testosterone level is 1300. I smoke Marijuana for depression.  My pens won’t fully balloon and seems to have leakage.  Also I leak pretty cum fluids only being half errect. During masterbation the ejaculate nerve seems real intense and I ejaculate quick and then I’m able to ejaculate again without being errect.  Help, what can I do? My sec life is at an all time low.

Dr. Lin’s Answer:
Although your T10-T12 sympathetic nerves do  interfere with your erectile function to some degrees,  marijuana THC causes erectile function by blunting your central dopamine, norepinephrine and epinephrine nervous responses to stimulation.  This means THC also knocks down your sympathetic nervous function.
The erectile function depends on the central dopamine nervous action on the NOergic , vagus/parasympathetic and sympathetic nerve,  while androgen hormones testosterone and DHT are just for maintaining the integrity of the erectile smooth muscle. This can explain while your high testosterone level won’t give you a proper sexual response.
You should quit marijuana, and take ViaPal-hGH-P(3-010) and ArgiNOx (1-018), plus Omega-3  Fish Oil(2-005) and Vitamin D (2-004),  to help you gradually rejuvenate your dopamine nervous function and  boost your prostaglandin E-1/E-3 and Nitric Oxide production for healing.  This formula is for antidepression too.

PS: During copulation, dopamine plays the key role for the brain and genital arousal.Dopamine-Mating-Exhaustion

Peyronies Disease – Deformation or hardening of genital smooth muscle

Peyronies Disease – Deformation or hardening of genital smooth muscle with uneven distribution of collagen scar tissues over the smooth muscle

Peyronies Disease is generally referred to the male genital deformation, but women have the similar problem – deformation, thinning or hardening of the genitourinary smooth muscle, which results in incontinence,  dryness, looseness, prolapse, dyspareunia or vaginismus, although it is invisible.

OK, first let’s consider the male problem.

The penile smooth muscle, like arterial ones,  can repair or regrow itself  via the stem cell’s  transforming growth factor-beta(3) (TGF-beta3) which regrows the local cells like embryo does . However, due to the penile blood flow restriction, or androgen hormone deficiency, or excessive drug toxins, there are insufficient active stem cells around the damaged tissue to release TGF-beta3  for regenerating the smooth muscle.  As a result, The damaged  (also, “nutritionally starved” ) cell  releases collagen protein, and activates cellular transforming growth factor-beta(1) (TGF-beta1) for a faster reconstruction and  reconnection of the damaged tissue.  This will further restrict the genitourinary blood circulation for more deformation, shrinkage, scarring and thinning of the smooth muscle. Ref: http://www.ncbi.nlm.nih.gov/pubmed/15291880

Chemical or mechanical damage, or degeneration of penile smooth muscles due to deficiency of androgen hormones (testosterone and/or DHT) or/and erectile factors ( nitric oxide (NO) and prostaglandins), is likely to disable the stem cells which result in activation of TGF-beta1 instead  of TGF-beta3. The embryo TGF-beta3 can multiply or duplicate the smooth muscle cells without a presence of collagen scar tissues.  Embryo TGF-beta3 helps a baby heal any wounds or cuts without any scars. As we get old, we will have less and less TGF-beta3, in particular,  in the genital smooth muscle cells which requires a lot of human growth hormones, androgen hormones, nitric oxide and prostaglandins to maintain the integrity of the smooth muscle.  If you can increase the cellular TGF-beta3 activities in the smooth muscle, you can or repair or regrow it, like a baby and puberty teenager does.

Chemical damage of penile tissues can be caused by medication or street drugs, diabetes, high stress hormones or prolactin,  and deficiency of oxytocin, hGH, DHEA, testosterone and DHT in the bloodstream.  The most destruction medication drugs for the penile smooth muscle include the beta blocker, 5-alpha reductase inhibitors (for hair regrowth or prostate enlargement), and LDL cholesterol lowering drugs.  Beta blockers constrict the penile arteries for poor blood circulation; 5-alpha reductase inhibitors cause DHT deficiency; the LDL lowering drugs result in deficiency of DHEA, testosterone and DHT.  On the other hands, all the street drugs are likely to cause severe damage of the smooth muscle by either disabling the hypothalamus-pituitary-testicular axis, killing the erectile nerves, enhancing the inflammatory hormone prostaglandin E2 synthesis while reducing the synthesis of other prostaglandins,  or even poisoning the adult stem cells.

Mechanical damage of the penile smooth muscle is very common for men who practice penile stretching or pumping.  When the smooth muscle matrix is forcefully stretched or expanded beyond its elastic capacity, collagen protein is released in an attempt to repair the damaged smooth tissue. In stead of repair, collagen protein hardens the damaged spot.   In addition to the over-strained damage, the smooth muscle can become fatigue when the tissue is subject to high-frequency vibration, even if the amplitude is small. Collagen protein starts to release all over the smooth muscle when the smooth muscle become fatigue.  This will result in reduction of the erectile ability of the smooth muscle, ending up with with hardening and shrinkage. Vibrator abusers, men or women, are likely to experience erectile dysfunction of the smooth muscle in the penis, urethra, clitoris or vagina. It also destroys or hardens the vagus nerve, leading to urinary or bowling incontinence.

The smooth muscle can become hardened in certain zones or spots.   For men, the collagen scar formation produces a crooked/bent or hour-glass shaped penis. For women, it results in external genital shrinkage and hardening, thinning (or scarring) of urethral and vaginal smoothing muscle, and vaginal enlargement. This is the female Peyronies Disease!  Since the female genital smooth muscle is hidden above the pelvic flood muscle, women won’t be aware of the Peyronies Disease even if they experience incontinence,  dryness, looseness, prolapse, dyspareunia or vaginismus!

Once we understand the causes of the problem, we can re-model them by activating the adult stem cells in the smooth muscle for TGF-beta3, accordingly:

1. take need ViaPal-hGH-P(3-010) and ArgiNOx (1-018), plus Omega-3  Fish Oil(2-005) and Vitamin D (2-004),  to help you gradually rejuvenate your neuro-endocrine function (increaseing testosterone and DHT level) and  boost your prostaglandin E-1/E-3 and Nitric Oxide production for healing. http://linstitute.apollohosting.com/store/index.html

(why should you maintain an above-averaged androgen hormone level?  please read
“Effects of Androgen on the Expression of Vascular Endothelial Growth Factor in the Penile Corpus Cavernosum”
by Eu Chang Hwanga, Kyung Jin Oha, Seung Il Junga, Noel N. Kimb, Kyu Youn Ahnc, and Kwangsung Park,
Urology, Volume 77, Issue 6, June 2011, Pages 1381–1386
http://www.sciencedirect.com/science/article/pii/S0090429511001099 )

2. Practice genital ballooning and massage with VIP Cream (1-015) to increase the smooth muscle blood flow, to stimulate the NO and prostaglandins release, and to  soften the hardened tissues. http://www.actionlove.com/WordPress/2014/02/25/theory-of-penile-ballooning-enlargement/  or

Noticeably, we have also developed the G-spot Ballooning method for women to rejuvenate and regrow the smooth muscle, as described in http://www.actionlove.com/WordPress/2015/08/14/g-spot-rejuvenation-and-natural-regrowth/

There are a lot of other benefits, as described in this article entitled: “How to perform Vagus Nerve Stimulation (VNS) from your bottom (pelvic floor) with VIP Cream , of course, without an electronic pulse generator?”  http://www.actionlove.com/WordPress/2016/01/09/how-to-perform-vagus-nerve-stimulation-vns-from-your-bottom-pelvic-floor-with-vip-cream-of-course-without-an-electronic-pulse-generator/

By the way, if you can not take ViaPal-hGH-P, you can switch to ViaPal-hGH-M (3-014), ViaPal-hGH-E (3-011), or ViaPal-hGH-S (3-013) instead.  You want to boost dopamine, but can not take ViaPla-hGH-P, you can switch to ViaPal-hGH-A (3-020) or ViaPal-hGH-F (3-022).  You can find a suitable formula from http://linstitute.apollohosting.com/store/index.html

Or send it e-mail over from http://www.taonetworks.net/mailform.html


  1.  Dulak J1, Józkowicz A, Dembinska-Kiec A, Guevara I, Zdzienicka A, Zmudzinska-Grochot D, Florek I, Wójtowicz A, Szuba A, and Cooke JP., ” Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells.” Arterioscler Thromb Vasc Biol. 2000 Mar;20(3):659-66. http://atvb.ahajournals.org/content/20/3/659.full.pdf+html
  2.  Eu Chang Hwanga, Kyung Jin Oha, Seung Il Junga, Noel N. Kimb, Kyu Youn Ahnc, and Kwangsung Park,  “Effects of Androgen on the Expression of Vascular Endothelial Growth Factor in the Penile Corpus Cavernosum”
    Urology, Volume 77, Issue 6, June 2011, Pages 1381–1386
  3. Yamanaka M1, Shirai M, Shiina H, Tanaka Y, Enokida H, Tsujimura A, Matsumiya K, Okuyama A, and Dahiya R.,
    “Vascular endothelial growth factor restores erectile function through inhibition of apoptosis in diabetic rat penile crura.”  J Urol. 2005 Jan;173(1):318-23.
  4.  Shirai M1, Yamanaka M, Shiina H, Igawa M, Kawakami T, Ishii N, Lue TF, Fujime M, and Dahiya R., “Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat.” Biochem Biophys Res Commun. 2006 Mar 17;341(3):755-62. Epub 2006 Jan 19.
  5. Lin CS1, Lue TF., “Growth factor therapy and neuronal nitric oxide synthase.” Int J Impot Res. 2004 Jun;16 Suppl 1:S38-9. http://www.ncbi.nlm.nih.gov/pubmed/15224135
  6. Toda N1, Ayajiki K, and Okamura T, “Nitric oxide and penile erectile function. ” Pharmacol Ther. 2005 May;106(2):233-66. Epub 2005 Mar 2. http://www.ncbi.nlm.nih.gov/pubmed/15866322
  7.  Kingston PA1, Sinha S, Appleby CE, David A, Verakis T, Castro MG, Lowenstein PR, and Heagerty AM, “Adenovirus-mediated gene transfer of transforming growth factor-beta3, but not transforming growth factor-beta1, inhibits constrictive remodeling and reduces luminal loss after coronary angioplasty.” Circulation. 2003 Dec 2;108(22):2819-25. Epub 2003 Nov 24. http://circ.ahajournals.org/content/108/22/2819.full.pdf+html
  8.  Deasy BM1, Feduska JM, Payne TR, Li Y, Ambrosio F, and Huard J, “Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle.”  Mol Ther. 2009 Oct;17(10):1788-98. doi: 10.1038/mt.2009.136. Epub 2009 Jul 14. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835014/pdf/mt2009136a.pdf
  9.  Beckman SA1, Chen WC, Tang Y, Proto JD, Mlakar L, Wang B, Huard J., “Beneficial effect of mechanical stimulation on the regenerative potential of muscle-derived stem cells is lost by inhibiting vascular endothelial growth factor. “Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):2004-12. doi: 10.1161/ATVBAHA.11http://www.ncbi.nlm.nih.gov/pubmed/23723372#2.301166. Epub 2013 May 30.  http://atvb.ahajournals.org/content/33/8/2004.full.pdf+html
  10.  Andrzejewski W, Kassolik K, Kobierzycki C1, Grzegrzolka J, Ratajczak-Wielgomas K, Jablonska K, Halski T, Dziegiel P, Gworys B, and Podhorska-Okolow M., “Increased skeletal muscle expression of VEGF induced by massage and exercise.”  Folia Histochem Cytobiol. 2015;53(2):145-51. doi: 10.5603/FHC.a2015.0013. Epub 2015 Jul 7.   https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/FHC.a2015.0013/29409
  11.  Best TM1, Gharaibeh B, and  Huard J. “Stem cells, angiogenesis and muscle healing: a potential role in massage therapies? ”  Br J Sports Med. 2013 Jun;47(9):556-60. doi: 10.1136/bjsports-2012-091685. Epub 2012 Nov 29.  http://www.ncbi.nlm.nih.gov/pubmed/23197410
  12. Cao H, Kang BJ, Lee CA, Shung KK, Hsiai TK., “Electrical and Mechanical Strategies to Enable Cardiac Repair and Regeneration.” IEEE Rev Biomed Eng. 2015;8:114-24. doi: 10.1109/RBME.2015.2431681. Epub 2015 May 11. http://www.ncbi.nlm.nih.gov/pubmed/25974948